RS/tRNA Foundational Publication Support
Takimoto, Jeffrey K, Katrina Adams, Zheng Xiang, and Lei Wang. (2009) 2009. “Improving Orthogonal Trna-Synthetase Recognition For Efficient Unnatural Amino Acid Incorporation And Application In Mammalian Cells.”. Molecular Biosystems 5 (9): 931-4. doi:10.1039/b904228h.
Parrish, Angela R, Xingyu She, Zheng Xiang, Irene Coin, Zhouxin Shen, Steven P Briggs, Andrew Dillin, and Lei Wang. (2012) 2012. “Expanding The Genetic Code Of Caenorhabditis Elegans Using Bacterial Aminoacyl-Trna Synthetase/Trna Pairs.”. Acs Chemical Biology 7 (7): 1292-302. doi:10.1021/cb200542j.
RS/tRNA Pair Development Year
2009
ncAA(s) Incorporated
O-methyl-L-tyrosine
ncAA Structure (png, jpg, jpeg)
ncAA Utility
Labelling of muscles
(global)
(global)
RS Organism of Origin
Parent RS
RS Mutations
Y37T
D182T
L183M
D265R
D182T
L183M
D265R
tRNA Organism of Origin
Parent tRNA
tRNA Anticodon
CUA
Other tRNA Mutations
N/A
RS/tRNA Availability
N/A
RS/tRNA Additional Notes
2012 foundational paper used the RS in C elegans.