2-bromo-L-phenylalanine

ncAA Structure (png, jpg, jpeg)
2-bromo-L-phenylalanine

ncAA Foundational Publication Support

Tharp, Jeffery M, Yane-Shih Wang, Yan-Jiun Lee, Yanyan Yang, and Wenshe R Liu. (2014) 2014. “Genetic Incorporation Of Seven Ortho-Substituted Phenylalanine Derivatives.”. Acs Chemical Biology 9 (4): 884-90. doi:10.1021/cb400917a.

ncAA Utility
n/a
ncAA Source
Exogenous - Purchased
ncAA Availability
Can be purchased https://www.thermofisher.com/order/catalog/product/H63141.03

RS/tRNA Pair Usage Information
Yielded ~47 mg/L GFPTAG2 when at 2 mM in E. coli using GMML media. Fidelity confirmed by MS. In LB media yielded 50 mg/L (~3 times that obtained with Phe) of GFPTAG27. No MS done. Appeared to be toxic to HEK293T when at 5 mM.

RS/tRNA Pair(s)


ncAA Synonyms
L-2-Bromophenylalanine
42538-40-9
2-Bromo-L-Phenylalanine
(S)-2-Amino-3-(2-bromophenyl)propanoic acid
2-Bromophenylalanine
(2S)-2-amino-3-(2-bromophenyl)propanoic acid
H-PHE(2-BR)-OH
o-Bromo-L-phenylalanine
DTXSID70173694
(2S)-2-azaniumyl-3-(2-bromophenyl)propanoate
ChEBI ID
233123