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endo-BCN-L-Lysine

endo-BCN-L-Lysine

ncAA Foundational Publication Support

Borrmann, Annika, Sigrid Milles, Tilman Plass, Jan Dommerholt, Jorge M M Verkade, Manfred Wiessler, Carsten Schultz, Jan C M van Hest, Floris L van Delft, and Edward A Lemke. (2012) 2012. “Genetic Encoding Of A Bicyclo[6.1.0]Nonyne-Charged Amino Acid Enables Fast Cellular Protein Imaging By Metal-Free Ligation.”. Chembiochem : A European Journal Of Chemical Biology 13 (14): 2094-9. doi:10.1002/cbic.201200407.

ncAA Protocols

Nikić, Ivana, Jun Hee Kang, Gemma Estrada Girona, Iker Valle Aramburu, and Edward A Lemke. (2015) 2015. “Labeling Proteins On Live Mammalian Cells Using Click Chemistry.”. Nature Protocols 10 (5): 780-91. doi:10.1038/nprot.2015.045.
ncAA Utility
Reactive handle for SPAAC
ncAA Source
Exogenous - Purchased
ncAA Availability
Can be purchased from https://www.medchemexpress.com/endo-bcn-l-lysine.html
Also:
endoBCN is SiChem catalog number SC8016
exoBCN is SiChem catalog 8014
racemicBCN is SiChem catalog number SC8003

RS/tRNA Pair(s)

ncAA Synonyms
(Rac)-BCN-L-Lysine
bicyclo[6.1.0]nonyne-lysine
SCHEMBL16748971
ChEBI ID
233067
ChEBI Link
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI%3A233067&conversationCont…