l-Cys-e-Lys

N6-L -Cysteinyl-L-lysine

ncAA Foundational Publication Support

Nguyen, Duy P, Thomas Elliott, Matthew Holt, Tom W Muir, and Jason W Chin. (2011) 2011. “Genetically Encoded 1,2-Aminothiols Facilitate Rapid and Site-Specific Protein Labeling via a Bio-Orthogonal Cyanobenzothiazole Condensation”. Journal of the American Chemical Society 133 (30): 11418-21. doi:10.1021/ja203111c.

ncAA Utility

Condenses with 2-cyanobenzothiazole for protein modification.

ncAA Source

Exogenous - Synthesized

ncAA Availability

N/A

RS/tRNA Pair(s)

MmPylRS-WT

RS/tRNA Pair Development Year

2009

RS Organism of Origin

Methanosarcina mazei

CysKRS

RS/tRNA Pair Development Year

2011

RS Organism of Origin

Methanosarcina barkeri

ncAA Synonyms

Nε-l-Cysteinyl-l-lysine

ChEBI ID

233663

ChEBI Link

https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI%3A233663&conversationCont…