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p-isopropyl-L-phenylalanine

p-Isopropyl-L phenylalanine

ncAA Foundational Publication Support

Santoro, Stephen W, Lei Wang, Brad Herberich, David S King, and Peter G Schultz. (2002) 2002. “An Efficient System For The Evolution Of Aminoacyl-Trna Synthetase Specificity.”. Nature Biotechnology 20 (10): 1044-8.
Young, Douglas D, Travis S Young, Michael Jahnz, Insha Ahmad, Glen Spraggon, and Peter G Schultz. (2011) 2011. “An Evolved Aminoacyl-Trna Synthetase With Atypical Polysubstrate Specificity.”. Biochemistry 50 (11): 1894-900. doi:10.1021/bi101929e.
ncAA Utility
tyrosine analog
ncAA Source
Endogenous
ncAA Availability
can be brought from https://www.sigmaaldrich.com/US/en/product/achemblock/advh0430a373?context=bbe
RS/tRNA Pair Usage Information
need to replace dummy RS with pIF RS from 2002 foundational paper

RS/tRNA Pair(s)

ncAA Synonyms
(S)-2-AMINO-3-(4-ISOPROPYL-PHENYL)PROPIONIC ACID
L-Phenylalanine,4-(1-methylethyl)-
(S)-2-AMINO-3-(4-ISOPROPYLPHENYL)PROPANOIC ACID
(2S)-2-amino-3-(4-propan-2-ylphenyl)propanoic acid
ChEBI ID
232656
ChEBI Link
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI%3A232656&conversationCont…
PubChem Link
https://pubchem.ncbi.nlm.nih.gov/compound/13406764