ncAA Structure (png, jpg, jpeg)
ncAA Foundational Publication Support
Zhang, Meng, Shixian Lin, Xinwen Song, Jun Liu, Ye Fu, Xi Ge, Xinmiao Fu, Zengyi Chang, and Peng R Chen. (2011) 2011. “A Genetically Incorporated Crosslinker Reveals Chaperone Cooperation In Acid Resistance.”. Nature Chemical Biology 7 (10): 671-7. doi:10.1038/nchembio.644.
ncAA Utility
Photo-crosslinker
ncAA Source
Exogenous - Purchased
ncAA Availability
Can be purchased from https://www.medchemexpress.com/DiZPK.html
RS/tRNA Pair Usage Information
works in E coli and mammalian cells, and available from Addgene
ncAA Synonyms
DiZPK
BCP15789
2-amino-6-({[3-(3-methyldiazirin-3-yl)propyl]carbamoyl}amino)hexanoic acid
BCP15789
2-amino-6-({[3-(3-methyldiazirin-3-yl)propyl]carbamoyl}amino)hexanoic acid
ChEBI ID
233064
PubChem Link
ncAA Additional Notes
shown in foundational publication to give much more efficient crosslinking (~80% vs. ~40%) than Bpa did for a particular E. coli protein studied.