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DiZHSeC

dizhsec

ncAA Foundational Publication Support

Yang, Yi, Haiping Song, Dan He, Shuai Zhang, Shizhong Dai, Shixian Li, Rong Meng, Chu Wang, and Peng Chen. (2017) 2016. “Genetically Encoded Protein Photocrosslinker With A Transferable Mass Spectrometry-Identifiable Label”. Nature Communications. doi:https://doi.org/10.1038/ncomms12299.

ncAA Protocols

Ye, Yang, Haiping Song, and Dan He. (2017) 2017. “Genetically Encoded Releasable Photo-Cross-Linking Strategies For Studying Protein–Protein Interactions In Living Cells”. Nature Communications. doi:https://doi.org/10.1038/nprot.2017.090.
ncAA Utility
photo-affinity crosslinker with a built-in, transferable mass spectrometry label.
ncAA Source
Exogenous - Synthesized
ncAA Availability
Synthesized in paper
RS/tRNA Pair Usage Information
Used with DZKRS, which is the same RS/tRNA pair as for DiZPK. Used in E. coli at 330 uM concentration and mammalian at 1mM concentration.

RS/tRNA Pair(s)

ncAA Synonyms
DiZHSeC
2230724-46-4
(S)-2-amino-4-((3-((3-(3-methyl-3H-diazirin-3-yl)propyl)amino)-3-oxopropyl)selanyl)butanoic acid
orb2566402
HY-D1032
DS-019198
CS-0030119
(2S)-2-amino-4-[3-[3-(3-methyldiazirin-3-yl)propylamino]-3-oxopropyl]selanylbutanoic acid
ChEBI ID
747357
ChEBI Link
https://www.ebi.ac.uk/chebi/CHEBI:747357
PubChem Link
https://pubchem.ncbi.nlm.nih.gov/compound/DiZHSeC
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