GCE Publications

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2022 Generation of Photocaged Nanobodies for Intracellular Applications in an Animal Using Genetic Code Expansion and Computationally Guided Protein Engineering. Jack O'Shea, Angeliki Goutou, Jack Brydon, Cyrus Sethna, Christopher Wood, Sebastian Greiss
2022 The tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism. Haolin Zhang, Xuemei Gong, Qianqian Zhao, Takahito Mukai, Oscar Vargas-Rodriguez, Huiming Zhang, Yuxing Zhang, Paul Wassel, Kazuaki Amikura, Julie Maupin-Furlow, Yan Ren, Xun Xu, Yuri Wolf, Kira Makarova, Eugene Koonin V, Yue Shen, Dieter Söll, Xian Fu
2022 Uncover New Reactivity of Genetically Encoded Alkyl Bromide Non-Canonical Amino Acids. Xin Shu, Sana Asghar, Fan Yang, Shang-Tong Li, Haifan Wu, Bing Yang
2022 Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding. Kelsey Kean, Stefanie Baril, Kelsey Lamb, Sarah Dishman, Joseph Treacy, Kendall Houk, Eric Brustad, Lindsey James, Marcey Waters
2022 Recent Advances in Fluorescence Imaging by Genetically Encoded Non-canonical Amino Acids. Sanghee Lee, Jonghoon Kim, Minseob Koh
2022 Genetic Code Expansion: Another Solution to Codon Assignments. Kensaku Sakamoto
2022 Rational incorporation of any unnatural amino acid into proteins by machine learning on existing experimental proofs. Haoran Zhang, Zhetao Zheng, Liangzhen Dong, Ningning Shi, Yuelin Yang, Hongmin Chen, Yuxuan Shen, Qing Xia
2022 The complete chloroplast genome of the medical plant Huperzia crispata from the Huperziaceae family: structure, comparative analysis, and phylogenetic relationships. Dengpan Yin, Bo Pang, Haibo Li, Qiao Liu, Yufeng Zhai, Nan Ma, Tongtong Chen, Hongjun Shen, Qiaojun Jia, Dekai Wang
2022 Site-specific Incorporation of Phosphoserine into Recombinant Proteins in . Phillip Zhu, Ryan Mehl, Richard Cooley
2022 Expanding the chemical diversity of M13 bacteriophage. Grace Allen, Ashley Grahn, Katerina Kourentzi, Richard Willson, Sean Waldrop, Jiantao Guo, Brian Kay
2022 Tuning the Properties of Protein-Based Polymers Using High-Performance Orthogonal Translation Systems for the Incorporation of Aromatic Non-Canonical Amino Acids. Osher Gueta, Ortal Sheinenzon, Rotem Azulay, Hadas Shalit, Daniela Strugach, Dagan Hadar, Sigal Gelkop, Anat Milo, Miriam Amiram
2022 Expanding the functionality of proteins with genetically encoded dibenzo[,][1,4,5]thiadiazepine: a photo-transducer for photo-click decoration. Qin Xiong, Tingting Zheng, Xin Shen, Baolin Li, Jielin Fu, Xiaohu Zhao, Chunxia Wang, Zhipeng Yu
2022 Directed Evolution Pipeline for the Improvement of Orthogonal Translation Machinery for Genetic Code Expansion at Sense Codons. Wil Biddle, David Schwark, Margaret Schmitt, John Fisk
2022 Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue. Yingzi Tan, Miao Wang, Yijun Chen
2021 Selection and validation of orthogonal tRNA/synthetase pairs for the encoding of unnatural amino acids across kingdoms. Grace Galles, Daniel Infield, Ryan Mehl, Christopher Ahern
2021 A Genetically Encoded Isonitrile Lysine for Orthogonal Bioorthogonal Labeling Schemes. Ágnes Szatmåri, Gergely Cserép, Tibor Molnår, Bianka Söveges, Adrienn Biró, György Vårady, Edit Szabó, Krisztina Németh, Péter Kele
2021 A high-performance genetically encoded fluorescent biosensor for imaging physiological peroxynitrite. Zhijie Chen, Shen Zhang, Xinyu Li, Hui-Wang Ai
2021 Effect of C-terminus Conjugation via Different Conjugation Chemistries on In Vivo Activity of Albumin-Conjugated Recombinant GLP-1. Junyong Park, Mijeong Bak, Kiyoon Min, Hyun-Woo Kim, Jeong-Haeng Cho, Giyoong Tae, Inchan Kwon
2021 Genetic Code Expansion Tools to Study Lysine Acylation Petra Neumann-Staubitz, Michael Lammers, Heinz Neumann
2021 Assays to Study Enzymatic and Non-Enzymatic Protein Lysine Acetylation In Vitro. Leonie Graf, Robert Vogt, Anna-Theresa Blasl, Chuan Qin, Sabrina Schulze, Daniela ZĂŒhlke, Susanne Sievers, Michael Lammers
2021 Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation. Christopher Reinkemeier, Edward Lemke
2021 Ion channel engineering using protein trans-splicing. Debayan Sarkar, Hendrik Harms, Iacopo Galleano, Zeshan Sheikh, Stephan Pless
2021 Synthesis and Evaluation of Novel Ring-Strained Noncanonical Amino Acids for Residue-Specific Bioorthogonal Reactions in Living Cells. Christopher Reinkemeier, Christine Koehler, Paul Sauter, Nataliia Shymanska V, Cecile Echalier, Anna Rutkowska, David Will, Carsten Schultz, Edward Lemke
2021 Efficient Preparation and Bioactivity Evaluation of Glycan-Defined Glycoproteins. Ji Hyun, Sanggil Kim, Chang-Hee Lee, Hyun Lee, Injae Shin
2021 Recent advancements in enzyme engineering via site-specific incorporation of unnatural amino acids. Hang-Qin Zhu, Xiao-Ling Tang, Ren-Chao Zheng, Yu-Guo Zheng