GCE Publications

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2024 Generation of site-specifically labelled fluorescent human XPA to investigate DNA binding dynamics during nucleotide excision repair. Sahiti Kuppa, Elliot Corless, Colleen Caldwell, Maria Spies, Edwin Antony
2024 Electrochemical labelling of hydroxyindoles with chemoselectivity for site-specific protein bioconjugation. Conor Loynd, Soumya Roy, Vincent Ovalle, Sarah Canarelli, Atanu Mondal, Delilah Jewel, Elise Ficaretta, Eranthie Weerapana, Abhishek Chatterjee
2024 Selective nitration of Hsp90 acts as a metabolic switch promoting tumor cell proliferation. Isabelle Logan, Kyle Nguyen, Tilottama Chatterjee, Bhagyashree Manivannan, Ngozi Paul, Sharon Kim, Evelyn Sixta, Lydia Bastian, Carrie Marean-Reardon, Matthias Karajannis, Cristina Fernández-Valle, Alvaro Estevez, Maria Franco
2024 Partial wrapping of single-stranded DNA by replication protein A and modulation through phosphorylation. Rahul Chadda, Vikas Kaushik, Iram Ahmad, Jaigeeth Deveryshetty, Alex Holehouse, Snorri Sigurdsson, Gargi Biswas, Yaakov Levy, Brian Bothner, Richard Cooley, Ryan Mehl, Reza Dastvan, Sofia Origanti, Edwin Antony
2024 Directed Evolution of a Bacterial Leucyl tRNA in Mammalian Cells for Enhanced Noncanonical Amino Acid Mutagenesis. Rachel Huang, Delilah Jewel, Rachel Kelemen, Quan Pham, Tarah Yared, Shu Wang, Soumya Roy, Zeyi Huang, Samantha Levinson, Bharathi Sundaresh, Suyen Miranda, Tim van Opijnen, Abhishek Chatterjee
2024 Secondary Amine Catalysis in Enzyme Design: Broadening Protein Template Diversity through Genetic Code Expansion. Thomas Williams, Irshad Taily, Lewis Hatton, Andrey Berezin, Yi-Lin Wu, Vicent Moliner, Katarzyna Åšwiderek, Yu-Hsuan Tsai, Louis Luk
2024 Orthogonal Translation for Site-Specific Installation of Post-translational Modifications. Qinglei Gan, Chenguang Fan
2024 An efficient pyrrolysyl-tRNA synthetase for economical production of MeHis-containing enzymes. Amy Hutton, Jake Foster, James Sanders, Christopher Taylor, Stefan Hoffmann, Yizhi Cai, Sarah Lovelock, Anthony Green
2024 Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion. Maria Weyh, Marie-Lena Jokisch, Tuan-Anh Nguyen, Maximilian Fottner, Kathrin Lang
2024 Non-canonical amino acids uncover the significant impact of Tyr671 on Taq DNA polymerase catalytic activity. Wanyi Chen, Binbin Chen, Xinjia Li, Gang Xu, Lirong Yang, Jianping Wu, Haoran Yu
2024 Applications of genetic code expansion technology in eukaryotes. Qiao-Ru Guo, Yu Cao
2024 Domain coupling in activation of a family C GPCR. Naomi Latorraca, Sam Sabaat, Chris Habrian, Julia Bleier, Cherise Stanley, Susan Marqusee, Ehud Isacoff
2024 Genetically Encoded Photocaged Proteinogenic and Non-Proteinogenic Amino Acids. Xiaochen Yang, Xun-Cheng Su, Weimin Xuan
2024 Insights into the dynamics of the Ca2+ release-activated Ca2+ channel pore-forming complex Orai1. Maximilian Fröhlich, Julia Söllner, Isabella Derler
2024 Pinpointing Acidic Residues in Proteins. Weimin Xuan, Jun-An Ma
2023 Genetic code expansion reveals aminoacylated lysine ubiquitination mediated by UBE2W Jia Zang, Yulin Chen, Chao Liu, Linzhen Hu, Hongxia Zhao, Wenlong Ding, Ying Yuan, Shixian Lin
2023 Advances in Biosynthesis of Non-Canonical Amino Acids (ncAAs) and the Methods of ncAAs Incorporation into Proteins. Liang Chen, Xiulan Xin, Yuning Zhang, Shunyao Li, Xiaoman Zhao, Song Li, Zhaochu Xu
2023 Covalent Proteins as Targeted Radionuclide Therapies Enhance Antitumor Effects. Paul Klauser, Shalini Chopra, Li Cao, Kondapa Bobba, Bingchen Yu, Youngho Seo, Emily Chan, Robert Flavell, Michael Evans, Lei Wang
2023 Reprogramming Initiator and Nonsense Codons to Simultaneously Install Three Distinct Noncanonical Amino Acids into Proteins in E. coli. Han-Kai Jiang, Jeffery Tharp
2023 Bioorthogonal Tethering Enhances Drug Fragment Affinity for G Protein-Coupled Receptors in Live Cells. Jordan Mattheisen, Chris Limberakis, Roger Ruggeri, Matthew Dowling, Christopher Ende, Emilie Ceraudo, Thomas Huber, Christopher McClendon, Thomas Sakmar
2023 Linking chromatin acylation mark-defined proteome and genome in living cells. Fangfei Qin, Boyuan Li, Hui Wang, Sihui Ma, Jiaofeng Li, Shanglin Liu, Linghao Kong, Huangtao Zheng, Rongfeng Zhu, Yu Han, Mingdong Yang, Kai Li, Xiong Ji, Peng Chen
2023 7SK methylation by METTL3 promotes transcriptional activity Marcelo Perez-Pepe, Anthony Desotell, Hengyi Li, Wenxue Li, Bing Han, Qishan Lin, Daryl Klein, Yansheng Liu, Hani Goodarzi, Claudio Alarcón
2023 A New PETase from the Human Saliva Metagenome and Its Functional Modification via Genetic Code Expansion in Bacteria. Mirren White, Stephen Wallace
2023 Non-Canonical Amino Acids in Analyses of Protease Structure and Function. Peter Goettig, Nikolaj Koch, Nediljko Budisa
2023 Establishing the fundamental rules for genetic code expansion. Souvik Sinha, Mohd Ahsan, Giulia Palermo