GCE Publications

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2024 Bacteria employ lysine acetylation of transcriptional regulators to adapt gene expression to cellular metabolism. Magdalena Kremer, Sabrina Schulze, Nadja Eisenbruch, Felix Nagel, Robert Vogt, Leona Berndt, Babett Dörre, Gottfried Palm, Jens Hoppen, Britta Girbardt, Dirk Albrecht, Susanne Sievers, Mihaela Delcea, Ulrich Baumann, Karin Schnetz, Michael Lammers
2024 Differential superoxide production in phosphorylated neuronal nitric oxide synthase mu and alpha variants. Yadav Gyawali, Ting Jiang, Jing Yang, Huayu Zheng, Rui Liu, Haikun Zhang, Changjian Feng
2024 Selective nitration of Hsp90 acts as a metabolic switch promoting tumor cell proliferation. Isabelle Logan, Kyle Nguyen, Tilottama Chatterjee, Bhagyashree Manivannan, Ngozi Paul, Sharon Kim, Evelyn Sixta, Lydia Bastian, Carrie Marean-Reardon, Matthias Karajannis, Cristina Fernández-Valle, Alvaro Estevez, Maria Franco
2024 Partial wrapping of single-stranded DNA by replication protein A and modulation through phosphorylation. Rahul Chadda, Vikas Kaushik, Iram Ahmad, Jaigeeth Deveryshetty, Alex Holehouse, Snorri Sigurdsson, Gargi Biswas, Yaakov Levy, Brian Bothner, Richard Cooley, Ryan Mehl, Reza Dastvan, Sofia Origanti, Edwin Antony
2024 Reading and Writing the Ubiquitin Code Using Genetic Code Expansion. Rishi Patel, Nipuni Pannala, Chittaranjan Das
2024 Generation of site-specifically labelled fluorescent human XPA to investigate DNA binding dynamics during nucleotide excision repair. Sahiti Kuppa, Elliot Corless, Colleen Caldwell, Maria Spies, Edwin Antony
2024 Electrochemical labelling of hydroxyindoles with chemoselectivity for site-specific protein bioconjugation. Conor Loynd, Soumya Roy, Vincent Ovalle, Sarah Canarelli, Atanu Mondal, Delilah Jewel, Elise Ficaretta, Eranthie Weerapana, Abhishek Chatterjee
2024 Directed Evolution of a Bacterial Leucyl tRNA in Mammalian Cells for Enhanced Noncanonical Amino Acid Mutagenesis. Rachel Huang, Delilah Jewel, Rachel Kelemen, Quan Pham, Tarah Yared, Shu Wang, Soumya Roy, Zeyi Huang, Samantha Levinson, Bharathi Sundaresh, Suyen Miranda, Tim van Opijnen, Abhishek Chatterjee
2024 Secondary Amine Catalysis in Enzyme Design: Broadening Protein Template Diversity through Genetic Code Expansion. Thomas Williams, Irshad Taily, Lewis Hatton, Andrey Berezin, Yi-Lin Wu, Vicent Moliner, Katarzyna Åšwiderek, Yu-Hsuan Tsai, Louis Luk
2024 Orthogonal Translation for Site-Specific Installation of Post-translational Modifications. Qinglei Gan, Chenguang Fan
2024 Domain coupling in activation of a family C GPCR. Naomi Latorraca, Sam Sabaat, Chris Habrian, Julia Bleier, Cherise Stanley, Susan Marqusee, Ehud Isacoff
2024 An efficient pyrrolysyl-tRNA synthetase for economical production of MeHis-containing enzymes. Amy Hutton, Jake Foster, James Sanders, Christopher Taylor, Stefan Hoffmann, Yizhi Cai, Sarah Lovelock, Anthony Green
2024 Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion. Maria Weyh, Marie-Lena Jokisch, Tuan-Anh Nguyen, Maximilian Fottner, Kathrin Lang
2024 Non-canonical amino acids uncover the significant impact of Tyr671 on Taq DNA polymerase catalytic activity. Wanyi Chen, Binbin Chen, Xinjia Li, Gang Xu, Lirong Yang, Jianping Wu, Haoran Yu
2024 Applications of genetic code expansion technology in eukaryotes. Qiao-Ru Guo, Yu Cao
2023 Design principles for engineering light-controlled antibodies. Eike Joest, Robert Tampé
2023 Site-specific dual encoding and labeling of proteins via genetic code expansion. Riley Bednar, Andrew Karplus, Ryan Mehl
2023 Fluorescent human RPA to track assembly dynamics on DNA. Vikas Kaushik, Rahul Chadda, Sahiti Kuppa, Nilisha Pokhrel, Abhinav Vayyeti, Scott Grady, Chris Arnatt, Edwin Antony
2023 New Strategies for Probing the Biological Functions of Protein Post-translational Modifications in Mammalian Cells with Genetic Code Expansion. Wenlong Ding, Hongxia Zhao, Yulin Chen, Shixian Lin
2023 The Dysferlin C2A Domain Binds PI(4,5)P2 and Penetrates Membranes. Ethiene Kwok, Shauna Otto, Patricia Khuu, Andrew Carpenter, Sara Codding, Patrick Reardon, Juan Vanegas, Tanushri Kumar, Chapman Kuykendall, Ryan Mehl, Joe Baio, Colin Johnson
2023 Encoding Noncanonical Amino Acids into Phage Displayed Proteins. Cristina Díaz-Perlas, Montserrat Escobar-Rosales, Charles Morgan, Benjamí Oller-Salvia
2023 Autonomous Synthesis of Functional, Permanently Phosphorylated Proteins for Defining the Interactome of Monomeric 14-3-3ζ. Phillip Zhu, Stanislau Stanisheuski, Rachel Franklin, Amber Vogel, Cat Vesely, Patrick Reardon, Nikolai Sluchanko, Joseph Beckman, Andrew Karplus, Ryan Mehl, Richard Cooley
2023 Optimized genetic code expansion technology for time-dependent induction of adhesion GPCR-ligand engagement. Marcel Streit, Mareike Hemberger, Stephanie Häfner, Felix Knote, Tobias Langenhan, Gerti Beliu
2023 Enabling Genetic Code Expansion and Peptide Macrocyclization in mRNA Display via a Promiscuous Orthogonal Aminoacyl-tRNA Synthetase. Sabrina Iskandar, Jarrett Pelton, Elizaveta Wick, Derek Bolhuis, Albert Baldwin, Michael Emanuele, Nicholas Brown, Albert Bowers
2023 Genetic Code Expansion in Mammalian Cells Through Quadruplet Codon Decoding. Yan Chen, Tianyu Gao, Xinyuan He, Wei Niu, Jiantao Guo