GCE Publications

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2023 Non-canonical amino acid incorporation into AAV5 capsid enhances lung transduction in mice. Hao Chang, Ailing Du, Jun Jiang, Lingzhi Ren, Nan Liu, Xuntao Zhou, Jialing Liang, Guangping Gao, Dan Wang
2023 Genetic Encoding of Arylazopyrazole Phenylalanine for Optical Control of Translation. Chasity Janosko, Olivia Shade, Taylor Courtney, Trevor Horst, Melinda Liu, Sagar Khare, Alexander Deiters
2023 Selective Inhibition of Kinase Activity in Mammalian Cells by Bioorthogonal Ligand Tethering. Jinghao Chen, Yang Huang, Wen-Biao Gan, Yu-Hsuan Tsai
2023 Shedding light on ORAI1 channel with genetic code expansion. Sher Ali, Guolin Ma, Yubin Zhou
2023 Residue selective crosslinking of proteins through photoactivatable or proximity-enabled reactivity. Jun Liu, Bing Yang, Lei Wang
2023 Genetic encoding of 3-nitro-tyrosine reveals the impacts of 14-3-3 nitration on client binding and dephosphorylation. Phillip Zhu, Kyle Nguyen, Aidan Estelle, Nikolai Sluchanko, Ryan Mehl, Richard Cooley
2023 Enzyme redesign and genetic code expansion. Vaitea Opuu, Thomas Simonson
2023 Design principles for engineering light-controlled antibodies. Eike Joest, Robert Tampé
2023 Biosynthesis and Genetic Encoding of Non-hydrolyzable Phosphoserine into Recombinant Proteins in Escherichia coli. Phillip Zhu, Ryan Mehl, Richard Cooley
2023 Structural basis of ubiquitin-independent PP1 complex disassembly by p97 Johannes van den Boom, Guendalina Marini, Hemmo Meyer, Helen Saibil
2023 Use of non-canonical amino acids in genetic code expansion-based therapeutics: Effects on mouse gut microbiota. Manyu Liang, Yanhong Yang, Jing Zhang, Yingjie Sun, Haixia Peng, Huawei Yi, Qin Wang, Xiaowei Gao
2023 Redesigning methionyl-tRNA synthetase for β-methionine activity with adaptive landscape flattening and experiments. Vaitea Opuu, Giuliano Nigro, Christine Lazennec-Schurdevin, Yves Mechulam, Emmanuelle Schmitt, Thomas Simonson
2023 Conformational GPCR BRET Sensors Based on Bioorthogonal Labeling of Noncanonical Amino Acids. Maria Kowalski-Jahn, Hannes Schihada, Gunnar Schulte
2023 Controlled Genetic Encoding of Unnatural Amino Acids in a Protein Nanopore. Xue-Yuan Wu, Meng-Yin Li, Shao-Jun Yang, Jie Jiang, Yi-Lun Ying, Peng Chen, Yi-Tao Long
2023 An intact amber-free HIV-1 system for in-virus protein bioorthogonal click labeling that delineates envelope conformational dynamics. Yuanyun Ao, Jonathan Grover, Yang Han, Guohua Zhong, Wenyi Qin, Dibya Ghimire, Anzarul Haque, Rajanya Bhattacharjee, Baoshan Zhang, James Arthos, Edward Lemke, Peter Kwong, Maolin Lu
2023 Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and suppresses autoimmunity. Bo Zhang, Jiaqi Sun, Yeshuang Yuan, Dezhong Ji, Yeting Sun, Yudong Liu, Shengjie Li, Xingxing Zhu, Xunyao Wu, Jin Hu, Qiu Xie, Ling Wu, Lulu Liu, Boyang Cheng, Yuanjie Zhang, Lingjuan Jiang, Lidan Zhao, Fei Yu, Wei Song, Min Wang, Yue Xu, Shiliang Ma, Yunyun Fei, Lihe Zhang, Demin Zhou, Xuan Zhang
2023 Archeal tRNA meets biotechnology: From vaccines to genetic code expansion. Lluís de Pouplana
2023 Genetic Code Expansion in Mammalian Cells Through Quadruplet Codon Decoding. Yan Chen, Tianyu Gao, Xinyuan He, Wei Niu, Jiantao Guo
2023 Integrated Bioluminescent Immunoassays for High-Throughput Sampling and Continuous Monitoring of Cytokines Eva van Aalen, Bas Rosier, Tom Jansen, Simone Wouters, Robin Vermathen, Harmen van der Veer, José Lozano, Sheeza Mughal, Juan Fernández-Costa, Javier Ramón-Azcón, Jaap Toonder, Maarten Merkx
2023 Near Infrared Light-Triggered Photocatalytic Decaging for Remote-Controlled Spatiotemporal Activation in Living Mice. Xuan Liang, Shan Qian, Zhizheng Lou, Renming Hu, Yuchen Hou, Peng Chen, Xinyuan Fan
2023 Redirecting the JAK-STAT signal blocks the SARS-CoV-2 replication. George Augustine, Valappil Sisila, Mohan Indhu, Divya Gupta, Dixit Tandel, Krishnan Harshan, Ganesh Shanmugam, Padmanabhan Padmapriya, Srinivasan Sivasubramanian, Krishnaswamy Kaveri, Kamini Ramudu, Niraikulam Ayyadurai
2023 Genetically Encoded 1,2-Aminothiol for Site-Specific Modification of a Cellular Membrane Protein via TAMM Condensation. Han Sun, Yang Huang, Yu-Hsuan Tsai
2023 Minimizing the Anticodon-Recognized Loop of Tyrosyl-tRNA Synthetase to Improve the Efficiency of Incorporating Noncanonical Amino Acids. Zhiyang Hu, Jinming Liang, Taogeng Su, Di Zhang, Hao Li, Xiangdong Gao, Wenbin Yao, Xiaoda Song
2023 An Efficient Opal-Suppressor Tryptophanyl Pair Creates New Routes for Simultaneously Incorporating up to Three Distinct Noncanonical Amino Acids into Proteins in Mammalian Cells. Arianna Osgood, Yunan Zheng, Soumya Roy, Nikolaos Biris, Myer Hussain, Conor Loynd, Delilah Jewel, James Italia, Abhishek Chatterjee
2023 Chemically Acylated tRNAs are Functional in Zebrafish Embryos. Wes Brown, Jason Galpin, Carolyn Rosenblum, Michael Tsang, Christopher Ahern, Alexander Deiters