GCE Publications

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2023 Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues. Christopher Taylor, Florence Hardy, Ashleigh Burke, Riley Bednar, Ryan Mehl, Anthony Green, Sarah Lovelock
2023 Capturing Covalent Catalytic Intermediates by Enzyme Mutants: Recent Advances in Methodologies and Applications. Yongchao Wang, Shan Tang
2023 Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family. Sören Kirchgäßner, Michael Braun, Natascha Bartlick, Cengiz Koç, Christopher Reinkemeier, Edward Lemke, Thilo Stehle, Dirk Schwarzer
2023 Engineering enzyme activity using an expanded amino acid alphabet. Zachary Birch-Price, Christopher Taylor, Mary Ortmayer, Anthony Green
2023 On the origin of the genetic code. Masayuki Seki
2023 Functional analysis of protein post-translational modifications using genetic codon expansion. Tao Peng, Tandrila Das, Ke Ding, Howard Hang
2023 The Expanded Central Dogma: Genome Resynthesis, Orthogonal Biosystems, Synthetic Genetics. Karola Gerecht, Niklas Freund, Wei Liu, Yang Liu, Maximilian Fürst, Philipp Holliger
2023 Genetic Code Expansion for Site-Specific Labeling of Antibodies with Radioisotopes. Christine Koehler, Paul Sauter, Benedikt Klasen, Christopher Waldmann, Stefanie Pektor, Nicole Bausbacher, Edward Lemke, Matthias Miederer
2023 Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies Islam J, Conroy P, Fercher C, Kim M, Yaari Z, Jones M, Bell Tdm, Caradoc-Davies T, Law R, Whisstock J, Heller D, Mahler S, Corrie S
2023 Bioconjugation of a Fibroblast Activation Protein Targeted Interleukin-4. Matthias Ruopp, Sha Zhu, Rafael Worschech, Dorothee Haas, Simone Maschauer, Olaf Prante, Lorenz Meinel, Tessa Lühmann
2023 An unnatural enzyme with endonuclease activity towards small non-coding RNAs. Noreen Ahmed, Nadine Ahmed, Didier Bilodeau, John Pezacki
2023 Creating Selenocysteine-Specific Reporters Using Inteins. Christina Chung, Dieter Söll, Natalie Krahn
2023 Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic Archaeon ISO4-G1 and Its Structure-Based Engineering for Highly-Productive Cell-Free Genetic Code Expansion with Non-Canonical Amino Acids. Tatsuo Yanagisawa, Eiko Seki, Hiroaki Tanabe, Yoshifumi Fujii, Kensaku Sakamoto, Shigeyuki Yokoyama
2023 Co-translational Installation of Posttranslational Modifications by Non-canonical Amino Acid Mutagenesis. Wei Niu, Jiantao Guo
2023 High-yield recombinant bacterial expression of C-, N-labeled, serine-16 phosphorylated, murine amelogenin using a modified third generation genetic code expansion protocol. Garry Buchko, Mowei Zhou, Cat Vesely, Jinhui Tao, Wendy Shaw, Ryan Mehl, Richard Cooley
2022 Recent Advances in Genetic Code Expansion: From Cell Engineering to Protein Design. Tao Liu
2022 Intragenic codon usage in proteobacteria: Translational selection, IS expansion and genomic shrinkage. Anders Fuglsang
2022 Direct Capsid Labeling of Infectious HIV-1 by Genetic Code Expansion Allows Detection of Largely Complete Nuclear Capsids and Suggests Nuclear Entry of HIV-1 Complexes via Common Routes. Sandra Schifferdecker, Vojtech Zila, Thorsten Müller, Volkan Sakin, Maria Anders-Össwein, Vibor Laketa, Hans-Georg Kräusslich, Barbara Müller
2022 Substitution of the sole tryptophan of the cupredoxin, amicyanin, with 5-hydroxytryptophan alters fluorescence properties and energy transfer to the type 1 copper site. Anthony Pastore, Elise Ficaretta, Abhishek Chatterjee, Victor Davidson
2022 A Light-Activatable Photocaged Variant of the Ultra-High Affinity ALFA-Tag Nanobody. Benedikt Jedlitzke, Henning Mootz
2022 Site-Specific Protein Modification with Reducing Carbohydrates. Qifan Wu, Weidong Dong, Hui Miao, Qian Wang, Suwei Dong, Weimin Xuan
2022 Chemoselective restoration of para-azido-phenylalanine at multiple sites in proteins. Pol Arranz-Gibert, Koen Vanderschuren, Adrian Haimovich, Anushka Halder, Kallol Gupta, Jesse Rinehart, Farren Isaacs
2022 A designed photoenzyme for enantioselective [2+2] cycloadditions. Jonathan Trimble, Rebecca Crawshaw, Florence Hardy, Colin Levy, Murray Brown, Douglas Fuerst, Derren Heyes, Richard Obexer, Anthony Green
2022 A method to map the interaction network of the nuclear lamina with genetically encoded photo-crosslinkers . Petra Neumann-Staubitz, Daniel Kitsberg, Amnon Buxboim, Heinz Neumann
2022 Overexpression of recombinant proteins containing non-canonical amino acids in Vibrio natriegens: p-azido-L-phenylalanine as coupling site for 19F-tags Karina Stadler, Walter Becker, Barbara Darnhofer, Ruth Birner-Gruenberger, Klaus Zangger