GCE Publications

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2023 Enabling Genetic Code Expansion and Peptide Macrocyclization in mRNA Display via a Promiscuous Orthogonal Aminoacyl-tRNA Synthetase. Sabrina Iskandar, Jarrett Pelton, Elizaveta Wick, Derek Bolhuis, Albert Baldwin, Michael Emanuele, Nicholas Brown, Albert Bowers
2023 Genetic Code Expansion in Mammalian Cells Through Quadruplet Codon Decoding. Yan Chen, Tianyu Gao, Xinyuan He, Wei Niu, Jiantao Guo
2023 Design principles for engineering light-controlled antibodies. Eike Joest, Robert Tampé
2023 Genetic code expansion reveals aminoacylated lysine ubiquitination mediated by UBE2W Jia Zang, Yulin Chen, Chao Liu, Linzhen Hu, Hongxia Zhao, Wenlong Ding, Ying Yuan, Shixian Lin
2023 Advances in Biosynthesis of Non-Canonical Amino Acids (ncAAs) and the Methods of ncAAs Incorporation into Proteins. Liang Chen, Xiulan Xin, Yuning Zhang, Shunyao Li, Xiaoman Zhao, Song Li, Zhaochu Xu
2023 Covalent Proteins as Targeted Radionuclide Therapies Enhance Antitumor Effects. Paul Klauser, Shalini Chopra, Li Cao, Kondapa Bobba, Bingchen Yu, Youngho Seo, Emily Chan, Robert Flavell, Michael Evans, Lei Wang
2023 Reprogramming Initiator and Nonsense Codons to Simultaneously Install Three Distinct Noncanonical Amino Acids into Proteins in E. coli. Han-Kai Jiang, Jeffery Tharp
2023 Bioorthogonal Tethering Enhances Drug Fragment Affinity for G Protein-Coupled Receptors in Live Cells. Jordan Mattheisen, Chris Limberakis, Roger Ruggeri, Matthew Dowling, Christopher Ende, Emilie Ceraudo, Thomas Huber, Christopher McClendon, Thomas Sakmar
2023 Linking chromatin acylation mark-defined proteome and genome in living cells. Fangfei Qin, Boyuan Li, Hui Wang, Sihui Ma, Jiaofeng Li, Shanglin Liu, Linghao Kong, Huangtao Zheng, Rongfeng Zhu, Yu Han, Mingdong Yang, Kai Li, Xiong Ji, Peng Chen
2022 Site-specific Incorporation of Phosphoserine into Recombinant Proteins in . Phillip Zhu, Ryan Mehl, Richard Cooley
2022 Expanding the chemical diversity of M13 bacteriophage. Grace Allen, Ashley Grahn, Katerina Kourentzi, Richard Willson, Sean Waldrop, Jiantao Guo, Brian Kay
2022 Tuning the Properties of Protein-Based Polymers Using High-Performance Orthogonal Translation Systems for the Incorporation of Aromatic Non-Canonical Amino Acids. Osher Gueta, Ortal Sheinenzon, Rotem Azulay, Hadas Shalit, Daniela Strugach, Dagan Hadar, Sigal Gelkop, Anat Milo, Miriam Amiram
2022 Expanding the functionality of proteins with genetically encoded dibenzo[,][1,4,5]thiadiazepine: a photo-transducer for photo-click decoration. Qin Xiong, Tingting Zheng, Xin Shen, Baolin Li, Jielin Fu, Xiaohu Zhao, Chunxia Wang, Zhipeng Yu
2022 Directed Evolution Pipeline for the Improvement of Orthogonal Translation Machinery for Genetic Code Expansion at Sense Codons. Wil Biddle, David Schwark, Margaret Schmitt, John Fisk
2022 Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue. Yingzi Tan, Miao Wang, Yijun Chen
2022 Engineered bacterial host for genetic encoding of physiologically stable protein nitration. Nikolaj Koch, Tobias Baumann, Jessica Nickling, Anna Dziegielewski, Nediljko Budisa
2022 Cryptochrome 1 as a state variable of the circadian clockwork of the suprachiasmatic nucleus: Evidence from translational switching. David McManus, Lenka Polidarova, Nicola Smyllie, Andrew Patton, Johanna Chesham, Elizabeth Maywood, Jason Chin, Michael Hastings
2022 A Photo-Crosslinking Approach to Identify Class II SUMO-1 Binders. Kira Brüninghoff, Stephanie Wulff, Wolfgang Dörner, Ruth Geiss-Friedlander, Henning Mootz
2022 Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining. Maria Cabello-Lobato, Matthew Jenner, Metztli Cisneros-Aguirre, Kira Brüninghoff, Zac Sandy, Isabelle da Costa, Thomas Jowitt, Christian Loch, Stephen Jackson, Qian Wu, Henning Mootz, Jeremy Stark, Matthew Cliff, Christine Schmidt
2022 Selective Inhibition of Cysteine-Dependent Enzymes by Bioorthogonal Tethering. Luke Spear, Yang Huang, Jinghao Chen, Alexander Nödling, Satpal Virdee, Yu-Hsuan Tsai
2022 Genetically encoding latent bioreactive amino acids and the development of covalent protein drugs. Nanxi Wang, Lei Wang
2022 New covalent bonding ability for proteins. Li Cao, Lei Wang
2022 Applications of Genetic Code Expansion in Studying Protein Post-translational Modification. Jinghao Chen, Yu-Hsuan Tsai
2022 Measuring Repeat-Associated Non-AUG (RAN) Translation. Shaopeng Wang, Shuying Sun
2022 Minimal genetically encoded tags for fluorescent protein labeling in living neurons. Aleksandra Arsić, Cathleen Hagemann, Nevena Stajković, Timm Schubert, Ivana Nikić-Spiegel