GCE Publications

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2018 Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells. Birthe Meineke, Johannes Heimgärtner, Lorenzo Lafranchi, Simon Elsässer
2018 Site-specific incorporation of quadricyclane into a protein and photocleavage of the quadricyclane ligation adduct. Frederick Tomlin, Chelsea Gordon, Yisu Han, Taia Wu, Ellen Sletten, Carolyn Bertozzi
2018 Expression and Purification of Site-Specifically Lysine-Acetylated and Natively-Folded Proteins for Biophysical Investigations. Michael Lammers
2018 In vitro genetic code reprogramming and expansion to study protein function and discover macrocyclic peptide ligands. Stacie Richardson, Kara Dods, Nicolas Abrigo, Emil Iqbal, Matthew Hartman
2018 Analysis of Reptarenavirus genomes indicates different selective forces acting on the S and L segments and recent expansion of common genotypes. Chiara Pontremoli, Diego Forni, Rachele Cagliani, Manuela Sironi
2018 Improved ontology for eukaryotic single-exon coding sequences in biological databases. Roddy Jorquera, Carolina González, Philip Clausen, Bent Petersen, David Holmes
2018 Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice. Elizabeth Maywood, Thomas Elliott, Andrew Patton, Toke Krogager, Johanna Chesham, Russell Ernst, Václav Beránek, Marco Brancaccio, Jason Chin, Michael Hastings
2018 A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation. Martin Baumdick, Márton Gelléri, Chayasith Uttamapinant, Václav Beránek, Jason Chin, Philippe Bastiaens
2018 Characterizing Lysine Acetylation of Isocitrate Dehydrogenase in Escherichia coli. Sumana Venkat, Hao Chen, Alleigh Stahman, Denver Hudson, Paige McGuire, Qinglei Gan, Chenguang Fan
2018 Genetic Code Expansion in Enteric Bacterial Pathogens. Huangtao Zheng, Shixian Lin, Peng Chen
2018 Genetic Code Expansion- and Click Chemistry-Based Site-Specific Protein Labeling for Intracellular DNA-PAINT Imaging. Ivana Nikić-Spiegel
2018 Comparative proteomics and codon substitution analysis reveal mechanisms of differential resistance to hypoxia in congeneric snails. Huawei Mu, Jin Sun, Siu Cheung, Ling Fang, Haiyun Zhou, Tiangang Luan, Huoming Zhang, Chris Wong, Jian-Wen Qiu
2017 Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection. Itthipol Sungwienwong, Zachary Hostetler, Robert Blizzard, Joseph Porter, Camden Driggers, Lea Mbengi, José Villegas, Lee Speight, Jeffery Saven, John Perona, Rahul Kohli, Ryan Mehl, James Petersson
2017 Non-additive stabilization by halogenated amino acids reveals protein plasticity on a sub-angstrom scale. Azade Hosseini, Christopher Pace, Adam Esposito, Jianmin Gao
2017 Precise Photoremovable Perturbation of a Virus-Host Interaction. Sarah Erickson, Raja Mukherjee, Rachel Kelemen, Chester Wrobel, Xiaofu Cao, Abhishek Chatterjee
2017 A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase. Jiaqi Lu, Hua Zhang, Xian Chen, Yong Zou, Jiasong Li, Li Wang, Minhao Wu, Jianye Zang, Yang Yu, Wei Zhuang, Qing Xia, Jiangyun Wang
2017 A genomically modified Escherichia coli strain carrying an orthogonal E. coli histidyl-tRNA synthetase•tRNA pair. Markus Englert, Oscar Vargas-Rodriguez, Noah Reynolds, Yane-Shih Wang, Dieter Söll, Takuya Umehara
2017 Continuous directed evolution of aminoacyl-tRNA synthetases David Bryson, Chenguang Fan, Li-Tao Guo, Corwin Miller, Dieter Söll, David Liu
2017 The Energetics of Chromophore Binding in the Visual Photoreceptor Rhodopsin. He Tian, Thomas Sakmar, Thomas Huber
2017 Site-Specific POxylation of Interleukin-4. Tessa LĂĽhmann, Marcel Schmidt, Meike Leiske, Valerie Spieler, Tobias Majdanski, Mandy Grube, Matthias Hartlieb, Ivo Nischang, Stephanie Schubert, Ulrich Schubert, Lorenz Meinel
2017 Site-Specific PEGylated Adeno-Associated Viruses with Increased Serum Stability and Reduced Immunogenicity. Tianzhuo Yao, Xueying Zhou, Chuanling Zhang, Xiaojuan Yu, Zhenyu Tian, Lihe Zhang, Demin Zhou
2017 Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R). Cassandra Koole, Christopher Reynolds, Juan Mobarec, Caroline Hick, Patrick Sexton, Thomas Sakmar
2017 Frozen Accident Pushing 50: Stereochemistry, Expansion, and Chance in the Evolution of the Genetic Code. Eugene Koonin V
2017 Chemical Tagging with tert-Butyl and Trimethylsilyl Groups for Measuring Intermolecular Nuclear Overhauser Effects in a Large Protein-Ligand Complex. Shereen Jabar, Luke Adams, Yao Wang, Luigi Aurelio, Bim Graham, Gottfried Otting
2017 Ubiquitin phosphorylated at Ser57 hyper-activates parkin. Susanna George, Sabrina Wang, Yumin Bi, Margot Treidlinger, Kathryn Barber, Gary Shaw, Patrick O'Donoghue