GCE Publications

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2012 Carbon source-dependent expansion of the genetic code in bacteria. Laure Prat, Ilka Heinemann, Hans Aerni, Jesse Rinehart, Patrick O'Donoghue, Dieter Söll
2012 Multiscale modeling of metabolism and macromolecular synthesis in E. coli and its application to the evolution of codon usage. Ines Thiele, Ronan Fleming, Richard Que, Aarash Bordbar, Dinh Diep, Bernhard Palsson
2012 Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA pairs. Angela Parrish, Xingyu She, Zheng Xiang, Irene Coin, Zhouxin Shen, Steven Briggs, Andrew Dillin, Lei Wang
2012 Ligation of expressed protein α-hydrazides via genetic incorporation of an α-hydroxy acid. Yi-Ming Li, Mai-Yun Yang, Yi-Chao Huang, Yi-Tong Li, Peng Chen, Lei Liu
2012 Microglial activation correlates with disease progression and upper motor neuron clinical symptoms in amyotrophic lateral sclerosis. Johannes Brettschneider, Jon Toledo, Vivianna Van Deerlin, Lauren Elman, Leo McCluskey, Virginia Lee, John Trojanowski
2012 Genetically encoded tetrazine amino acid directs rapid site-specific in vivo bioorthogonal ligation with trans-cyclooctenes. Jason Seitchik, Jennifer Peeler, Michael Taylor, Melissa Blackman, Timothy Rhoads, Richard Cooley, Christian Refakis, Joseph Fox, Ryan Mehl
2012 Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation. Annika Borrmann, Sigrid Milles, Tilman Plass, Jan Dommerholt, Jorge Verkade, Manfred Wiessler, Carsten Schultz, Jan van Hest, Floris van Delft, Edward Lemke
2012 Designer proteins: applications of genetic code expansion in cell biology. Lloyd Davis, Jason Chin
2012 A rationally designed pyrrolysyl-tRNA synthetase mutant with a broad substrate spectrum. Yane-Shih Wang, Xinqiang Fang, Ashley Wallace, Bo Wu, Wenshe Liu
2012 Wide-range protein photo-crosslinking achieved by a genetically encoded N(ε)-(benzyloxycarbonyl)lysine derivative with a diazirinyl moiety. Tatsuo Yanagisawa, Nobumasa Hino, Fumie Iraha, Takahito Mukai, Kensaku Sakamoto, Shigeyuki Yokoyama
2012 A rationally designed pyrrolysyl-tRNA synthetase mutant with a broad substrate spectrum. Yane-Shih Wang, Xinqiang Fang, Ashley Wallace, Bo Wu, Wenshe Liu
2012 Wide-range protein photo-crosslinking achieved by a genetically encoded N(ε)-(benzyloxycarbonyl)lysine derivative with a diazirinyl moiety. Tatsuo Yanagisawa, Nobumasa Hino, Fumie Iraha, Takahito Mukai, Kensaku Sakamoto, Shigeyuki Yokoyama
2012 A rationally designed pyrrolysyl-tRNA synthetase mutant with a broad substrate spectrum. Yane-Shih Wang, Xinqiang Fang, Ashley Wallace, Bo Wu, Wenshe Liu
2012 A rationally designed pyrrolysyl-tRNA synthetase mutant with a broad substrate spectrum. Yane-Shih Wang, Xinqiang Fang, Ashley Wallace, Bo Wu, Wenshe Liu
2012 A rationally designed pyrrolysyl-tRNA synthetase mutant with a broad substrate spectrum. Yane-Shih Wang, Xinqiang Fang, Ashley Wallace, Bo Wu, Wenshe Liu
2011 Crystallographic study of a site-specifically cross-linked protein complex with a genetically incorporated photoreactive amino acid. Shin Sato, Shinya Mimasu, Aya Sato, Nobumasa Hino, Kensaku Sakamoto, Takashi Umehara, Shigeyuki Yokoyama
2011 Improving a natural enzyme activity through incorporation of unnatural amino acids. Isaac Ugwumba, Kiyoshi Ozawa, Zhi-Qiang Xu, Fernanda Ely, Jee-Loon Foo, Anthony Herlt, Chris Coppin, Sue Brown, Matthew Taylor, David Ollis, Lewis Mander, Gerhard Schenk, Nicholas Dixon, Gottfried Otting, John Oakeshott, Colin Jackson
2011 RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sites. David Johnson, Jianfeng Xu, Zhouxin Shen, Jeffrey Takimoto, Matthew Schultz, Robert Schmitz, Zheng Xiang, Joseph Ecker, Steven Briggs, Lei Wang
2011 Association screening in the Epidermal Differentiation Complex (EDC) identifies an SPRR3 repeat number variant as a risk factor for eczema. Ingo Marenholz, Vladimir Rivera, Jorge Esparza-Gordillo, Anja Bauerfeind, Min-Ae Lee-Kirsch, Andrzej Ciechanowicz, Michael Kurek, Tereza Piskackova, Milan Macek, Young-Ae Lee
2011 Expanding the genetic code of Escherichia coli with phosphoserine. Hee-Sung Park, Michael Hohn, Takuya Umehara, Li-Tao Guo, Edith Osborne, Jack Benner, Christopher Noren, Jesse Rinehart, Dieter Söll
2011 In vivo incorporation of multiple noncanonical amino acids into proteins. Michael Hoesl, Nediljko Budisa
2011 A readily synthesized cyclic pyrrolysine analogue for site-specific protein "click" labeling. Ziyang Hao, Yanqun Song, Shixian Lin, Maiyun Yang, Yujie Liang, Jing Wang, Peng Chen
2011 A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance. Meng Zhang, Shixian Lin, Xinwen Song, Jun Liu, Ye Fu, Xi Ge, Xinmiao Fu, Zengyi Chang, Peng Chen
2011 Determinants of synonymous and nonsynonymous variability in three species of Drosophila. Penelope Haddrill, Kai Zeng, Brian Charlesworth
2011 The pyrrolysine translational machinery as a genetic-code expansion tool. Tomasz Fekner, Michael Chan