GCE Publications

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2024 An efficient pyrrolysyl-tRNA synthetase for economical production of MeHis-containing enzymes. Amy Hutton, Jake Foster, James Sanders, Christopher Taylor, Stefan Hoffmann, Yizhi Cai, Sarah Lovelock, Anthony Green
2024 Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion. Maria Weyh, Marie-Lena Jokisch, Tuan-Anh Nguyen, Maximilian Fottner, Kathrin Lang
2024 Non-canonical amino acids uncover the significant impact of Tyr671 on Taq DNA polymerase catalytic activity. Wanyi Chen, Binbin Chen, Xinjia Li, Gang Xu, Lirong Yang, Jianping Wu, Haoran Yu
2024 Applications of genetic code expansion technology in eukaryotes. Qiao-Ru Guo, Yu Cao
2024 Domain coupling in activation of a family C GPCR. Naomi Latorraca, Sam Sabaat, Chris Habrian, Julia Bleier, Cherise Stanley, Susan Marqusee, Ehud Isacoff
2024 Genetically Encoded Photocaged Proteinogenic and Non-Proteinogenic Amino Acids. Xiaochen Yang, Xun-Cheng Su, Weimin Xuan
2024 Insights into the dynamics of the Ca2+ release-activated Ca2+ channel pore-forming complex Orai1. Maximilian Fröhlich, Julia Söllner, Isabella Derler
2024 Pinpointing Acidic Residues in Proteins. Weimin Xuan, Jun-An Ma
2024 Reversing the charge of lysine by genetic code expansion. Daniela Danková, Christian Olsen
2024 tRNA engineering strategies for genetic code expansion. YouJin Kim, Suho Cho, Joo-Chan Kim, Hee-Sung Park
2024 Tracking endogenous proteins based on RNA editing-mediated genetic code expansion. Min Hao, Xinyu Ling, Yi Sun, Xue Wang, Wenzhe Li, Liying Chang, Zhiying Zeng, Xiaomeng Shi, Mengxiao Niu, Liangyi Chen, Tao Liu
2024 PCNA as Protein-Based Nanoruler for Sub-10 nm Fluorescence Imaging. Dominic Helmerich, Made Budiarta, Danush Taban, Sören Doose, Gerti Beliu, Markus Sauer
2024 Suppressor tRNAs at the interface of genetic code expansion and medicine. Aya Awawdeh, Alexander Radecki, Oscar Vargas-Rodriguez
2024 Unnatural Amino Acid-Based Ionic Liquid Enables Oral Treatment of Nonsense Mutation Disease in Mice. Yujie Shi, Ningning Shi, Yuelin Yang, Zhetao Zheng, Qing Xia
2024 Characterizing lysine acetylation of glucokinase. Nour Fatema, Xinyu Li, Qinglei Gan, Chenguang Fan
2023 Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies Islam J, Conroy P, Fercher C, Kim M, Yaari Z, Jones M, Bell Tdm, Caradoc-Davies T, Law R, Whisstock J, Heller D, Mahler S, Corrie S
2023 Bioconjugation of a Fibroblast Activation Protein Targeted Interleukin-4. Matthias Ruopp, Sha Zhu, Rafael Worschech, Dorothee Haas, Simone Maschauer, Olaf Prante, Lorenz Meinel, Tessa Lühmann
2023 An unnatural enzyme with endonuclease activity towards small non-coding RNAs. Noreen Ahmed, Nadine Ahmed, Didier Bilodeau, John Pezacki
2023 Creating Selenocysteine-Specific Reporters Using Inteins. Christina Chung, Dieter Söll, Natalie Krahn
2023 Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic Archaeon ISO4-G1 and Its Structure-Based Engineering for Highly-Productive Cell-Free Genetic Code Expansion with Non-Canonical Amino Acids. Tatsuo Yanagisawa, Eiko Seki, Hiroaki Tanabe, Yoshifumi Fujii, Kensaku Sakamoto, Shigeyuki Yokoyama
2023 Co-translational Installation of Posttranslational Modifications by Non-canonical Amino Acid Mutagenesis. Wei Niu, Jiantao Guo
2023 High-yield recombinant bacterial expression of C-, N-labeled, serine-16 phosphorylated, murine amelogenin using a modified third generation genetic code expansion protocol. Garry Buchko, Mowei Zhou, Cat Vesely, Jinhui Tao, Wendy Shaw, Ryan Mehl, Richard Cooley
2023 On the origin of the genetic code. Masayuki Seki
2023 Functional analysis of protein post-translational modifications using genetic codon expansion. Tao Peng, Tandrila Das, Ke Ding, Howard Hang
2023 The Expanded Central Dogma: Genome Resynthesis, Orthogonal Biosystems, Synthetic Genetics. Karola Gerecht, Niklas Freund, Wei Liu, Yang Liu, Maximilian Fürst, Philipp Holliger