GCE Publications

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2024 HIV-1 Capsid Uncoating Is a Multistep Process That Proceeds through Defect Formation Followed by Disassembly of the Capsid Lattice. Levi Gifford, Gregory Melikyan
2024 Genetic code expansion, click chemistry, and light-activated PI3K reveal details of membrane protein trafficking downstream of receptor tyrosine kinases. Duk-Su Koh, Anastasiia Stratiievska, Subhashis Jana, Shauna Otto, Teresa Swanson, Anthony Nhim, Sara Carlson, Marium Raza, Lígia Naves, Eric Senning, Ryan Mehl, Sharona Gordon
2024 Delivery of AKT1 phospho-forms to human cells reveals differential substrate selectivity. Tarana Siddika, Richard Shao, Ilka Heinemann, Patrick O'Donoghue
2024 Genetic Code Expansion in Pseudomonas putida KT2440. Tianyu Gao, Jiantao Guo, Wei Niu
2024 Bioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging. Yuanyun Ao, Jonathan Grover, Levi Gifford, Yang Han, Guohua Zhong, Revansiddha Katte, Wenwei Li, Rajanya Bhattacharjee, Baoshan Zhang, Stephanie Sauve, Wenyi Qin, Dibya Ghimire, Md Haque, James Arthos, Mahmoud Moradi, Walther Mothes, Edward Lemke, Peter Kwong, Gregory Melikyan, Maolin Lu
2023 Biosynthesis, Engineering, and Delivery of Selenoproteins. David Wright, Patrick O'Donoghue
2023 Site-specific photo-crosslinking/cleavage for protein-protein interface identification reveals oligomeric assembly of lysosomal-associated membrane protein type 2A in mammalian cells. Kazue Terasawa, Tatsuro Seike, Kensaku Sakamoto, Kazumasa Ohtake, Tohru Terada, Takanori Iwata, Tetsuro Watabe, Shigeyuki Yokoyama, Miki Hara-Yokoyama
2023 Extensive breaking of genetic code degeneracy with non-canonical amino acids. Clinton McFeely, Bipasana Shakya, Chelsea Makovsky, Aidan Haney, Ashton Cropp, Matthew Hartman
2023 Recoding UAG to selenocysteine in . Kyle Hoffman, Christina Chung, Takahito Mukai, Natalie Krahn, Han-Kai Jiang, Nileeka Balasuriya, Patrick O'Donoghue, Dieter Söll
2023 Optimization of genetic code expansion in the baculovirus expression vector system (BEVS). Ciarán Cronin
2023 Using the Noncanonical Metallo-Amino Acid [Cu(II)(2,2'-Bipyridin-5-yl)]-alanine to Study the Structures of Proteins. Leandro Tabares, Davis Daniel, José Vázquez-Ibar, Cyrille Kouklovsky, Valérie Alezra, Sun Un
2023 Dual incorporation of non-canonical amino acids enables production of post-translationally modified selenoproteins. Pearl Morosky, Cody Comyns, Lance Nunes, Christina Chung, Peter Hoffmann, Dieter Söll, Oscar Vargas-Rodriguez, Natalie Krahn
2023 A Versatile Strategy for Screening Custom-Designed Warhead-Armed Cyclic Peptide Inhibitors. Deokhee Kang, Do-Wook Kim, Joo-Chan Kim, Hee-Sung Park
2023 Genetic Code Expansion and a Photo-Cross-Linking Reaction Facilitate Ribosome Display Selections for Identifying a Wide Range of Affinity Peptides. Takuto Furuhashi, Kensaku Sakamoto, Akira Wada
2023 Discovery, implications and initial use of semi-synthetic organisms with an expanded genetic alphabet/code. Floyd Romesberg
2023 Ultra-Fast Bioorthogonal Spin-Labeling and Distance Measurements in Mammalian Cells Using Small, Genetically Encoded Tetrazine Amino Acids. Subhashis Jana, Eric Evans, Hyo Jang, Shuyang Zhang, Hui Zhang, Andrzej Rajca, Sharona Gordon, William Zagotta, Stefan Stoll, Ryan Mehl
2023 Rational design of the genetic code expansion toolkit for encoding of D-amino acids. Han-Kai Jiang, Jui-Hung Weng, Yi-Hui Wang, Jo-Chu Tsou, Pei-Jung Chen, An-Li Ko, Dieter Söll, Ming-Daw Tsai, Yane-Shih Wang
2023 Constructing Photoactivatable Protein with Genetically Encoded Photocaged Glutamic Acid. Xiaochen Yang, Lei Zhao, Ying Wang, Yanli Ji, Xun-Cheng Su, Jun-An Ma, Weimin Xuan
2023 Noncanonical Amino Acid Incorporation in Mice. Zhetao Zheng, Qing Xia
2023 Concerted conformational changes control metabotropic glutamate receptor activity. Nathalie Lecat-Guillet, Robert Quast, Hongkang Liu, Emmanuel Bourrier, Thor Møller, Xavier Rovira, Stéphanie Soldevila, Laurent Lamarque, Eric Trinquet, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard, Emmanuel Margeat
2023 Insights into receptor structure and dynamics at the surface of living cells. Frederik Steiert, Peter Schultz, Siegfried Höfinger, Thomas Müller, Petra Schwille, Thomas Weidemann
2023 Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14. Hezi Hayun, Matt Coban, Ashok Bhagat, Eden Ozer, Lital Alfonta, Thomas Caulfield, Evette Radisky, Niv Papo
2023 Selective incorporation of 5-hydroxytryptophan blocks long range electron transfer in oxalate decarboxylase. Anthony Pastore, Alvaro Montoya, Manasi Kamat, Kari Basso, James Italia, Abhishek Chatterjee, Maria Drosou, Dimitrios Pantazis, Alexander Angerhofer
2023 Site-Specific Introduction of Bioorthogonal Handles to Nanopores by Genetic Code Expansion. Jing Yang, Kefan Wang, Shanyu Zhang, Xiaocui Zheng, Tongxiao Cui, Xian Yang, Yao Liu, Di Lu, Yuqin Wang, Xiao Tian, Panke Zhang, Shuo Huang, Ran Xie
2023 Bacterial J-Domains with C-Terminal Tags Contact the Substrate Binding Domain of DnaK and Sequester Chaperone Activity Brock Nelson, Nathan Soper, Tania Lupoli