GCE Publications

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Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics I. Ali, R. Conrad, E. Verdin, M. Ott
Genetically Encoded Protein Phosphorylation in Mammalian Cells V. Beránek, C. Reinkemeier, M. Zhang, A. Liang, G. Kym, J. Chin
Histone recognition and large-scale structural analysis of the human bromodomain family P. Filippakopoulos, S. Picaud, M. Mangos, T. Keates, J. Lambert, D. Barsyte-Lovejoy, I. Felletar, R. Volkmer, S. Muller, T. Pawson
Lysine acetylation targets protein complexes and co-regulates major cellular functions C. Choudhary, C. Kumar, F. Gnad, M. Nielsen, M. Rehman, T. Walther, J. Olsen, M. Mann
Genetically encoding Nε-acetyllysine in recombinant proteins H. Neumann, S . Y. Peak-Chew, J. Chin
A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications E. Flynn, O. Huang, F. Poy, M. Oppikofer, S. Bellon, Y. Tang, A. Cochran
The growing landscape of lysine acetylation links metabolism and cell signalling C. Choudhary, B. Weinert, Y. Nishida, E. Verdin, M. Mann
Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair S. Hancock, R. Uprety, A. Deiters, J. Chin
Development of activity-based probes for the protein deacylase Sirt1 C. Goetz, D. Sprague, B. Smith
Functions and mechanisms of non-histone protein acetylation T. Narita, B. Weinert, C. Choudhary
Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair S. Hancock, R. Uprety, A. Deiters, J. Chin
Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC C. Tallant, E. Valentini, O. Fedorov, L. Overvoorde, F. Ferguson, P. Filippakopoulos, D. Svergun, S. Knapp, A. Ciulli
Targeting bromodomains: epigenetic readers of lysine acetylation P. Filippakopoulos, S. Knapp
Expanding the genetic code of Mus musculus S. Han, A. Yang, S. Lee, H.-W. Lee, C. Park, H.-S. Park
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase A. Brunet, L. Sweeney, J. Sturgill, K. Chua, P. Greer, Y. Lin, H. Tran, S. Ross, R. Mostoslavsky, H . Y. Cohen
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer T. Fujisawa, P. Filippakopoulos
A genetically encoded 19F NMR probe for lysine acetylation F. Zhang, Q. Zhou, G. Yang, L. An, F. Li, J. Wang
FOXO4 Is Acetylated upon Peroxide Stress and Deacetylated by the Longevity Protein hSir2SIRT1 A. van der Horst, L. Tertoolen, L. de Vries-Smits, R. Frye, R. Medema, B. Burgering
Bromodomains: a new target class for drug development A. Cochran, A. Conery, R. Sims
Sir2 Deacetylases Exhibit Nucleophilic Participation of Acetyl-Lysine in NAD+ Cleavage B. Smith, J. Denu
Regulation of FoxO activity by CBP/p300–mediated acetylation L. van der Heide, M. Smidt
A chemical toolbox for the study of bromodomains and epigenetic signaling Q. Wu, D. Heidenreich, S. Zhou, S. Ackloo, A. Krämer, K. Nakka, E. Lima-Fernandes, G. Deblois, S. Duan, R. Vellanki