GCE Publications

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2020 The Ancient Operational Code is Embedded in the Amino Acid Substitution Matrix and aaRS Phylogenies. Julia Shore, Barbara Holland, Jeremy Sumner, Kay Nieselt, Peter Wills
2020 An Expanded Genetic Code Enables Trimethylamine Metabolism in Human Gut Bacteria. Veronika Kivenson, Stephen Giovannoni
2020 RNA sectors and allosteric function within the ribosome. Allison Walker, William Russ, Rama Ranganathan, Alanna Schepartz
2020 Fast phosphine-activated control of protein function using unnatural lysine analogues. Joshua Wesalo, Alexander Deiters
2020 Site-Specific Protein Labeling with Fluorophores as a Tool To Monitor Protein Turnover. Yonatan Mideksa, Maximilian Fottner, Sebastian Braus, Caroline Weiß, Tuan-Anh Nguyen, Susanne Meier, Kathrin Lang, Matthias Feige
2020 Genetic code expansion in mammalian cells: A plasmid system comparison. Wenyuan Zhou, Joshua Wesalo, Jihe Liu, Alexander Deiters
2020 An Engineered Escherichia coli Strain with Synthetic Metabolism for in-Cell Production of Translationally Active Methionine Derivatives. Christian Schipp, Ying Ma, Ammar Al-Shameri, Federico D'Alessio, Peter Neubauer, Roberto Contestabile, Nediljko Budisa, Martino di Salvo
2020 Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1). Nileeka Balasuriya, Norman Davey, Jared Johnson, Huadong Liu, Kyle Biggar, Lewis Cantley, Shawn Li, Patrick O'Donoghue
2020 Live cell single molecule tracking and localization microscopy of bioorthogonally labeled plasma membrane proteins. Andres König, Raya Sorkin, Ariel Alon, Dikla Nachmias, Kalyan Dhara, Guy Brand, Ofer Yifrach, Eyal Arbely, Yael Roichman, Natalie Elia
2020 Natural pyrrolysine-biased translation of stop codons in mitochondrial peptides entirely coded by expanded codons. Hervé Seligmann, Ganesh Warthi
2020 Defining the Environmental Adaptations of Genus Devosia: Insights into its Expansive Short Peptide Transport System and Positively Selected Genes. Chandni Talwar, Shekhar Nagar, Roshan Kumar, Joy Scaria, Rup Lal, Ram Negi
2020 Linker and N-Terminal Domain Engineering of Pyrrolysyl-tRNA Synthetase for Substrate Range Shifting and Activity Enhancement Han-Kai Jiang, Man-Nee Lee, Jo-Chu Tsou, Kuan-Wen Chang, Hsueh-Wei Tseng, Kuang-Po Chen, Yaw-Kuen Li, Yane-Shih Wang
2020 An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli. Claudio Zambaldo, Minseob Koh, Fariborz Nasertorabi, Gye Han, Abhishek Chatterjee, Raymond Stevens, Peter Schultz
2020 The current chemical biology tool box for studying ion channels. N Braun, Z Sheikh, S Pless
2020 Generation of Recombinant Mammalian Selenoproteins through Genetic Code Expansion with Photocaged Selenocysteine. Jennifer Peeler, Julia Falco, Rachel Kelemen, Masahiro Abo, Benjamin Chartier V, Laura Edinger, Jingjia Chen, Abhishek Chatterjee, Eranthie Weerapana
2020 Identification of Human IDO1 Enzyme Activity by Using Genetically Encoded Nitrotyrosine. Zhaopeng Zheng, Xuzhen Guo, Minling Yu, Xiaoyan Wang, Hongguang Lu, Fahui Li, Jiangyun Wang
2020 Tackling Achilles' Heel in Synthetic Biology: Pairing Intracellular Synthesis of Noncanonical Amino Acids with Genetic-Code Expansion to Foster Biotechnological Applications. Hernán Biava
2020 Programmed ubiquitin acetylation using genetic code expansion reveals altered ubiquitination patterns. Rachel Lacoursiere, Patrick O'Donoghue, Gary Shaw
2020 Titrating bacterial growth and chemical biosynthesis for efficient N-acetylglucosamine and N-acetylneuraminic acid bioproduction. Rongzhen Tian, Yanfeng Liu, Yanting Cao, Zhongjie Zhang, Jianghua Li, Long Liu, Guocheng Du, Jian Chen
2020 Targeting interleukin-4 to the arthritic joint. Valerie Spieler, Marie-Gabrielle Ludwig, Janet Dawson, Bruno Tigani, Amanda Littlewood-Evans, Caterina Safina, Hilmar Ebersbach, Klaus Seuwen, Martina Raschig, Björn Mors, Thomas Müller, Lorenz Meinel, Tessa Lühmann
2020 Empowering Global Chemical Biology at the Dawn of the New Decade. Sascha Hoogendoorn, Yimon Aye
2020 A straightforward approach for bioorthogonal labeling of proteins and organelles in live mammalian cells, using a short peptide tag. Inbar Segal, Dikla Nachmias, Andres Konig, Ariel Alon, Eyal Arbely, Natalie Elia
2020 Genetically encoded protein sulfation in mammalian cells. James Italia, Jennifer Peeler, Christen Hillenbrand, Christopher Latour, Eranthie Weerapana, Abhishek Chatterjee
2020 Expanding the Scope of Orthogonal Translation with Pyrrolysyl-tRNA Synthetases Dedicated to Aromatic Amino Acids. Hsueh-Wei Tseng, Tobias Baumann, Huan Sun, Yane-Shih Wang, Zoya Ignatova, Nediljko Budisa
2020 Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs. Daniele Cervettini, Shan Tang, Stephen Fried, Julian Willis, Louise Funke, Lucy Colwell, Jason Chin