GCE Publications

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2018 A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation. Martin Baumdick, Márton Gelléri, Chayasith Uttamapinant, Václav Beránek, Jason Chin, Philippe Bastiaens
2018 Characterizing Lysine Acetylation of Isocitrate Dehydrogenase in Escherichia coli. Sumana Venkat, Hao Chen, Alleigh Stahman, Denver Hudson, Paige McGuire, Qinglei Gan, Chenguang Fan
2018 Genetic Code Expansion in Enteric Bacterial Pathogens. Huangtao Zheng, Shixian Lin, Peng Chen
2018 Genetic Code Expansion- and Click Chemistry-Based Site-Specific Protein Labeling for Intracellular DNA-PAINT Imaging. Ivana Nikić-Spiegel
2018 Comparative proteomics and codon substitution analysis reveal mechanisms of differential resistance to hypoxia in congeneric snails. Huawei Mu, Jin Sun, Siu Cheung, Ling Fang, Haiyun Zhou, Tiangang Luan, Huoming Zhang, Chris Wong, Jian-Wen Qiu
2018 Systematic Evaluation of Soluble Protein Expression Using a Fluorescent Unnatural Amino Acid Reveals No Reliable Predictors of Tolerability. Zachary Hostetler, John Ferrie, Marc Bornstein, Itthipol Sungwienwong, James Petersson, Rahul Kohli
2018 Directed Evolution of Heterologous tRNAs Leads to Reduced Dependence on Post-transcriptional Modifications. Kevin Baldridge, Manasses Jora, Andre Maranhao, Matthew Quick, Balasubrahmanyam Addepalli, Jennifer Brodbelt, Andrew Ellington, Patrick Limbach, Lydia Contreras
2018 Effects of Heterologous tRNA Modifications on the Production of Proteins Containing Noncanonical Amino Acids. Ana Crnković, Oscar Vargas-Rodriguez, Anna Merkuryev, Dieter Söll
2018 Type-II tRNAs and Evolution of Translation Systems and the Genetic Code. Yunsoo Kim, Bruce Kowiatek, Kristopher Opron, Zachary Burton
2018 Generation of Stable Amber Suppression Cell Lines. Simon Elsässer
2018 Characterization and comparative mitogenomic analysis of six newly sequenced mitochondrial genomes from ectomycorrhizal fungi (Russula) and phylogenetic analysis of the Agaricomycetes. Qiang Li, Qiangfeng Wang, Cheng Chen, Xin Jin, Zuqin Chen, Chuan Xiong, Ping Li, Jian Zhao, Wenli Huang
2018 RNA-Templated Concatenation of Triplet Nucleic-Acid Probe. Raman Bahal, Arunava Manna, Wei-Che Hsieh, Shivaji Thadke, Gopalsamy Sureshkumar, Danith Ly
2017 A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase. Jiaqi Lu, Hua Zhang, Xian Chen, Yong Zou, Jiasong Li, Li Wang, Minhao Wu, Jianye Zang, Yang Yu, Wei Zhuang, Qing Xia, Jiangyun Wang
2017 A genomically modified Escherichia coli strain carrying an orthogonal E. coli histidyl-tRNA synthetase•tRNA pair. Markus Englert, Oscar Vargas-Rodriguez, Noah Reynolds, Yane-Shih Wang, Dieter Söll, Takuya Umehara
2017 Continuous directed evolution of aminoacyl-tRNA synthetases David Bryson, Chenguang Fan, Li-Tao Guo, Corwin Miller, Dieter Söll, David Liu
2017 The Energetics of Chromophore Binding in the Visual Photoreceptor Rhodopsin. He Tian, Thomas Sakmar, Thomas Huber
2017 Site-Specific POxylation of Interleukin-4. Tessa Lühmann, Marcel Schmidt, Meike Leiske, Valerie Spieler, Tobias Majdanski, Mandy Grube, Matthias Hartlieb, Ivo Nischang, Stephanie Schubert, Ulrich Schubert, Lorenz Meinel
2017 Site-Specific PEGylated Adeno-Associated Viruses with Increased Serum Stability and Reduced Immunogenicity. Tianzhuo Yao, Xueying Zhou, Chuanling Zhang, Xiaojuan Yu, Zhenyu Tian, Lihe Zhang, Demin Zhou
2017 Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R). Cassandra Koole, Christopher Reynolds, Juan Mobarec, Caroline Hick, Patrick Sexton, Thomas Sakmar
2017 Frozen Accident Pushing 50: Stereochemistry, Expansion, and Chance in the Evolution of the Genetic Code. Eugene Koonin V
2017 Chemical Tagging with tert-Butyl and Trimethylsilyl Groups for Measuring Intermolecular Nuclear Overhauser Effects in a Large Protein-Ligand Complex. Shereen Jabar, Luke Adams, Yao Wang, Luigi Aurelio, Bim Graham, Gottfried Otting
2017 Ubiquitin phosphorylated at Ser57 hyper-activates parkin. Susanna George, Sabrina Wang, Yumin Bi, Margot Treidlinger, Kathryn Barber, Gary Shaw, Patrick O'Donoghue
2017 Tuning of Recombinant Protein Expression in Escherichia coli by Manipulating Transcription, Translation Initiation Rates, and Incorporation of Noncanonical Amino Acids. Orr Schlesinger, Yonatan Chemla, Mathias Heltberg, Eden Ozer, Ryan Marshall, Vincent Noireaux, Mogens Jensen, Lital Alfonta
2017 Origin and Evolution of the Universal Genetic Code. Eugene Koonin V, Artem Novozhilov
2017 A semisynthetic organism engineered for the stable expansion of the genetic alphabet. Yorke Zhang, Brian Lamb, Aaron Feldman, Anne Zhou, Thomas Lavergne, Lingjun Li, Floyd Romesberg