IodoPheRS (pIpaRS)

RS/tRNA Foundational Publication Support

Xie, Jianming, Lei Wang, Ning Wu, Ansgar Brock, Glen Spraggon, and Peter G Schultz. (2004) 2004. “The Site-Specific Incorporation Of P-Iodo-L-Phenylalanine Into Proteins For Structure Determination.”. Nature Biotechnology 22 (10): 1297-301.

Wang, Feng, Scott Robbins, Jiantao Guo, Weijun Shen, and Peter G Schultz. (2010) 2010. “Genetic Incorporation Of Unnatural Amino Acids Into Proteins In Mycobacterium Tuberculosis.”. Plos One 5 (2): e9354. doi:10.1371/journal.pone.0009354.

RS/tRNA Pair Development Year
2003

ncAA(s) Incorporated

p-iodo-L-phenylalanine

ncAA Structure (png, jpg, jpeg)
p-Iodo-L-phenylalanine
ncAA Utility
Can be used for phasing in protein crystallography.


RS Organism of Origin
Parent RS
RS Mutations
Y32L
E107S
D158P
I159L
L162E

tRNA Organism of Origin
Parent tRNA
tRNA Anticodon
CUA
Other tRNA Mutations
C17A
U17aG
U20C
G37A
U47G

RS/tRNA Availability
n/a
Used in what cell line?