RS/tRNA Foundational Publication Support
Neumann, Heinz, Sew Y Peak-Chew, and Jason W Chin. (2008) 2008. “Genetically Encoding N(Epsilon)-Acetyllysine In Recombinant Proteins.”. Nature Chemical Biology 4 (4): 232-4. doi:10.1038/nchembio.73.
RS/tRNA Pair Development Year
2008
ncAA(s) Incorporated
Nε-acetyl-L-lysine
ncAA Structure (png, jpg, jpeg)
ncAA Utility
They are used for sites specifically studying post-translational modification acetylation events on particular lysine residues.
RS Organism of Origin
Parent RS
RS Mutations
L270I
Y271L
L274A
C313F
Y271L
L274A
C313F
tRNA Organism of Origin
Parent tRNA
tRNA Anticodon
CUA
Other tRNA Mutations
N/A
Multiple tRNAs?
N/A
RS/tRNA Availability
n/a
Used in what cell line?
RS/tRNA Additional Notes
This RS was selected for but not characterized in the original paper. Only the MbAcKRS1 was characterized.