GCE Publications

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2022 The Pyrrolysyl-tRNA Synthetase Activity can be Improved by a P188 Mutation that Stabilizes the Full-Length Enzyme. Chia-Chuan Cho, Lauren Blankenship, Xinyu Ma, Shiqing Xu, Wenshe Liu
2022 Expansion of the genetic code through reassignment of redundant sense codons using fully modified tRNA. Clinton McFeely, Kara Dods, Shivam Patel, Matthew Hartman
2022 Editorial: Expansion of the Genetic Code: Unnatural Amino Acids and their Applications. Subhendu Bag, Ishu Saraogi, Jiantao Guo
2022 Nucleobase-modified nucleosides and nucleotides: Applications in biochemistry, synthetic biology, and drug discovery. Anthony Berdis
2022 Conformational fingerprinting of allosteric modulators in metabotropic glutamate receptor 2. Brandon Liauw, Arash Foroutan, Michael Schamber, Weifeng Lu, Hamid Afsari, Reza Vafabakhsh
2022 Generating Efficient Pyrrolysyl-tRNA Synthetases for Structurally Diverse Non-Canonical Amino Acids. Savanna Avila-Crump, Marcus Hemshorn, Chloe Jones, Lea Mbengi, Kyle Meyer, Joshua Griffis, Subhashis Jana, Grace Petrina, Vinayak Pagar V, Andrew Karplus, James Petersson, John Perona, Ryan Mehl, Richard Cooley
2022 Unconventional genetic code systems in archaea. Kexin Meng, Christina Chung, Dieter Söll, Natalie Krahn
2022 Optimizing eRF1 to Enable the Genetic Encoding of Three Distinct Noncanonical Amino Acids in Mammalian Cells. Ningning Shi, Le Tong, Haishuang Lin, Zhetao Zheng, Haoran Zhang, Liangzhen Dong, Yuelin Yang, Yuxuan Shen, Qing Xia
2022 Discovery of IL-5-binding unnatural cyclic peptides from multiple libraries by directed evolution. Daisuke Fuji, Takehiro Ando, Masashi Sato, Santhana Vedi, Yukio Takamori, Takumi Yokoyama, Mizuki Yamamoto, Takashi Kawakami
2022 Condensed, Microtubule-coating Thin Organelles for Orthogonal Translation in Mammalian Cells. Christopher Reinkemeier, Edward Lemke
2022 Substrate Profiling of Mitochondrial Caseinolytic Protease P via a Site-Specific Photocrosslinking Approach. Tuan-Anh Nguyen, Thomas Gronauer, Timon Nast-Kolb, Stephan Sieber, Kathrin Lang
2022 Complete chloroplast genome of Lilium ledebourii (Baker) Boiss and its comparative analysis: lights into selective pressure and adaptive evolution. Morteza Sheikh-Assadi, Roohangiz Naderi, Mohsen Kafi, Reza Fatahi, Seyed Salami, Vahid Shariati
2022 Peroxynitrite nitration of Tyr 56 in Hsp90 induces PC12 cell death through P2X7R-dependent PTEN activation. Megan Jandy, Asra Noor, Pascal Nelson, Cassandra Dennys, Isabella Karabinas, Jeanine Pestoni, Gautam Singh, Lam Luc, Rachel Devyldere, Nathalie Perdomo, Catherine Mitchell, Levi Adams, Marisa Fuse, Francine Mendoza, Carrie Marean-Reardon, Ryan Mehl, Alvaro Estevez, Maria Franco
2022 Mechanism of sensitivity modulation in the calcium-sensing receptor via electrostatic tuning. Michael Schamber, Reza Vafabakhsh
2021 Development of mammalian cell logic gates controlled by unnatural amino acids. Emily Mills, Victoria Barlow, Arwyn Jones, Yu-Hsuan Tsai
2021 Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids unveils masked epitopes in live neurons. Diogo Bessa-Neto, Gerti Beliu, Alexander Kuhlemann, Valeria Pecoraro, Sören Doose, Natacha Retailleau, Nicolas Chevrier, David Perrais, Markus Sauer, Daniel Choquet
2021 Bioorthogonal chemistry. Samuel Scinto, Didier Bilodeau, Robert Hincapie, Wankyu Lee, Sean Nguyen, Minghao Xu, Christopher Ende, M Finn, Kathrin Lang, Qing Lin, John Pezacki, Jennifer Prescher, Marc Robillard, Joseph Fox
2021 Single-molecule FRET and conformational analysis of beta-arrestin-1 through genetic code expansion and a Se-click reaction. Ming-Jie Han, Qing-Tao He, Mengyi Yang, Chao Chen, Yirong Yao, Xiaohong Liu, Yuchuan Wang, Zhong-Liang Zhu, Kong-Kai Zhu, Changxiu Qu, Fan Yang, Cheng Hu, Xuzhen Guo, Dawei Zhang, Chunlai Chen, Jin-Peng Sun, Jiangyun Wang
2021 Identification of Protein Direct Interactome with Genetic Code Expansion and Search Engine OpenUaa. Chao Liu, Ting Wu, Xin Shu, Shang-Tong Li, Daniel Wang, Nanxi Wang, Rong Zhou, Hao Yang, Hong Jiang, Ivo Hendriks, Pengyun Gong, Long Zhang, Michael Nielsen, Kui Li, Lei Wang, Bing Yang
2021 A Directed Evolution System for Lysine Deacetylases. Martin Spinck, Maria Ecke, Damian Schiller, Heinz Neumann
2021 Studying ion channel conformation dynamics by encoding coumarin as unnatural amino acid. Sebastian Brauchi, Ximena Steinberg
2021 When Supramolecular Chemistry Meets Chemical Biology: New Strategies to Target Proteins through Host-Guest Interactions. Wenbing Cao, Xuewen Qin, Tao Liu
2021 Conformational rearrangement during activation of a metabotropic glutamate receptor. Brandon Liauw, Hamid Afsari, Reza Vafabakhsh
2021 Succinylation profiles of brain injury after intracerebral hemorrhage. Yuan-Hong Deng, Xin-Xiao Zhang, Chuan-Yuan Tao, Yan-Jing Liang, Jing Yuan, Su-Hao Yang, Yuan-Rui Yang, Xiao-Yi Xiong
2021 Genetic Code Expansion in the Engineered Organism Vmax X2: High Yield and Exceptional Fidelity. Sebasthian González, Omer Ad, Bhavana Shah, Zhongqi Zhang, Xizi Zhang, Abhishek Chatterjee, Alanna Schepartz