GCE Publications

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2022 Generation and Characterization of Site-Specifically Mono-Ubiquitylated p53. Alexandra Julier, Vanessa Radtke, Andreas Marx, Martin Scheffner
2022 Genetic code degeneracy is established by the decoding center of the ribosome. Shixin Ye, Jean Lehmann
2022 Rational incorporation of any unnatural amino acid into proteins by machine learning on existing experimental proofs. Haoran Zhang, Zhetao Zheng, Liangzhen Dong, Ningning Shi, Yuelin Yang, Hongmin Chen, Yuxuan Shen, Qing Xia
2022 The complete chloroplast genome of the medical plant Huperzia crispata from the Huperziaceae family: structure, comparative analysis, and phylogenetic relationships. Dengpan Yin, Bo Pang, Haibo Li, Qiao Liu, Yufeng Zhai, Nan Ma, Tongtong Chen, Hongjun Shen, Qiaojun Jia, Dekai Wang
2022 Enhanced access to the human phosphoproteome with genetically encoded phosphothreonine. Jack Moen, Kyle Mohler, Svetlana Rogulina, Xiaojian Shi, Hongying Shen, Jesse Rinehart
2022 Unleashing the potential of noncanonical amino acid biosynthesis to create cells with precision tyrosine sulfation. Yuda Chen, Shikai Jin, Mengxi Zhang, Yu Hu, Kuan-Lin Wu, Anna Chung, Shichao Wang, Zeru Tian, Yixian Wang, Peter Wolynes, Han Xiao
2022 Generating Efficient Pyrrolysyl-tRNA Synthetases for Structurally Diverse Non-Canonical Amino Acids. Savanna Avila-Crump, Marcus Hemshorn, Chloe Jones, Lea Mbengi, Kyle Meyer, Joshua Griffis, Subhashis Jana, Grace Petrina, Vinayak Pagar V, Andrew Karplus, James Petersson, John Perona, Ryan Mehl, Richard Cooley
2022 Genetic Code Expansion and Bio-Orthogonal Labeling Reveal Intact HIV-1 Capsids inside the Nucleus. Leo James
2022 Generation of Photocaged Nanobodies for Intracellular Applications in an Animal Using Genetic Code Expansion and Computationally Guided Protein Engineering. Jack O'Shea, Angeliki Goutou, Jack Brydon, Cyrus Sethna, Christopher Wood, Sebastian Greiss
2022 The tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism. Haolin Zhang, Xuemei Gong, Qianqian Zhao, Takahito Mukai, Oscar Vargas-Rodriguez, Huiming Zhang, Yuxing Zhang, Paul Wassel, Kazuaki Amikura, Julie Maupin-Furlow, Yan Ren, Xun Xu, Yuri Wolf, Kira Makarova, Eugene Koonin V, Yue Shen, Dieter Söll, Xian Fu
2022 Uncover New Reactivity of Genetically Encoded Alkyl Bromide Non-Canonical Amino Acids. Xin Shu, Sana Asghar, Fan Yang, Shang-Tong Li, Haifan Wu, Bing Yang
2022 Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding. Kelsey Kean, Stefanie Baril, Kelsey Lamb, Sarah Dishman, Joseph Treacy, Kendall Houk, Eric Brustad, Lindsey James, Marcey Waters
2022 Recent Advances in Fluorescence Imaging by Genetically Encoded Non-canonical Amino Acids. Sanghee Lee, Jonghoon Kim, Minseob Koh
2022 Genetic Code Expansion: Another Solution to Codon Assignments. Kensaku Sakamoto
2021 Studying Protein Tyrosine O-Sulfation in Mammalian Cells with Genetically Encoded Sulfotyrosine. Xinyuan He, Jiantao Guo, Wei Niu
2021 Designing efficient genetic code expansion in Bacillus subtilis to gain biological insights. Devon Stork, Georgia Squyres, Erkin Kuru, Katarzyna Gromek, Jonathan Rittichier, Aditya Jog, Briana Burton, George Church, Ethan Garner, Aditya Kunjapur
2021 Intracellular bioorthogonal labeling of glucagon receptor via tetrazine ligation. Yulin Tian, Ming Fang, Qing Lin
2021 Site-Specific Incorporation of a Photoactivatable Fluorescent Amino Acid. Juan Tang, Chenfei Yu, Axel Loredo, Yuda Chen, Han Xiao
2021 Genetic Code Expansion: A Brief History and Perspective. Mia Shandell, Zhongping Tan, Virginia Cornish
2021 A Genetically Encoded Isonitrile Lysine for Orthogonal Bioorthogonal Labeling Schemes. Ágnes Szatmári, Gergely Cserép, Tibor Molnár, Bianka Söveges, Adrienn Biró, György Várady, Edit Szabó, Krisztina Németh, Péter Kele
2021 A high-performance genetically encoded fluorescent biosensor for imaging physiological peroxynitrite. Zhijie Chen, Shen Zhang, Xinyu Li, Hui-Wang Ai
2021 Assays to Study Enzymatic and Non-Enzymatic Protein Lysine Acetylation In Vitro. Leonie Graf, Robert Vogt, Anna-Theresa Blasl, Chuan Qin, Sabrina Schulze, Daniela Zühlke, Susanne Sievers, Michael Lammers
2021 Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation. Christopher Reinkemeier, Edward Lemke
2021 Ion channel engineering using protein trans-splicing. Debayan Sarkar, Hendrik Harms, Iacopo Galleano, Zeshan Sheikh, Stephan Pless
2021 Synthesis and Evaluation of Novel Ring-Strained Noncanonical Amino Acids for Residue-Specific Bioorthogonal Reactions in Living Cells. Christopher Reinkemeier, Christine Koehler, Paul Sauter, Nataliia Shymanska V, Cecile Echalier, Anna Rutkowska, David Will, Carsten Schultz, Edward Lemke