GCE Publications

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Functions and mechanisms of non-histone protein acetylation T. Narita, B. Weinert, C. Choudhary
Expanding the genetic code of Mus musculus S. Han, A. Yang, S. Lee, H.-W. Lee, C. Park, H.-S. Park
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase A. Brunet, L. Sweeney, J. Sturgill, K. Chua, P. Greer, Y. Lin, H. Tran, S. Ross, R. Mostoslavsky, H . Y. Cohen
Targeting bromodomains: epigenetic readers of lysine acetylation P. Filippakopoulos, S. Knapp
A genetically encoded 19F NMR probe for lysine acetylation F. Zhang, Q. Zhou, G. Yang, L. An, F. Li, J. Wang
FOXO4 Is Acetylated upon Peroxide Stress and Deacetylated by the Longevity Protein hSir2SIRT1 A. van der Horst, L. Tertoolen, L. de Vries-Smits, R. Frye, R. Medema, B. Burgering
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer T. Fujisawa, P. Filippakopoulos
Sir2 Deacetylases Exhibit Nucleophilic Participation of Acetyl-Lysine in NAD+ Cleavage B. Smith, J. Denu
Regulation of FoxO activity by CBP/p300–mediated acetylation L. van der Heide, M. Smidt
Bromodomains: a new target class for drug development A. Cochran, A. Conery, R. Sims
Acetyl-lysine Analog Peptides as Mechanistic Probes of Protein Deacetylases B. Smith, J. Denu
Regulation of FoxO transcription factors by acetylation and protein–protein interactions H. Daitoku, J.-i. Sakamaki, A. Fukamizu
A chemical toolbox for the study of bromodomains and epigenetic signaling Q. Wu, D. Heidenreich, S. Zhou, S. Ackloo, A. Krämer, K. Nakka, E. Lima-Fernandes, G. Deblois, S. Duan, R. Vellanki
Mechanism-Based Inhibition of Sir2 Deacetylases by Thioacetyl-Lysine Peptide B. Smith, J. Denu
Polyspecific pyrrolysyl-tRNA synthetases from directed evolution L.-T. Guo, Y.-S. Wang, A. Nakamura, D. Eiler, J. Kavran, M. Wong, L. Kiessling, T. Steitz, P. O’Donoghue, D. Söll
Target Structure–Based Discovery of Small Molecules that Block Human p53 and CREB Binding Protein Association null Sachchidanand, L. Resnick-Silverman, S. Yan, S. Mutjaba, W.-j. Liu, L. Zeng, J. Manfredi, M.–M. Zhou
A short guide to histone deacetylases including recent progress on class II enzymes S . Y. Park, J. Kim
N-Acetyl lysyl-tRNA synthetases evolved by a CcdB-based selection possess N-acetyl lysine specificity in vitro and in vivo T. Umehara, J. Kim, S. Lee, L.-T. Guo, D. Söll, H.-S. Park
Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes J. Lamonica, W. Deng, S. Kadauke, A. Campbell, R. Gamsjaeger, H. Wang, Y. Cheng, A. Billin, R. Hardison, J. Mackay
Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases A. Lahm, C. Paolini, M. Pallaoro, M. Nardi, P. Jones, P. Neddermann, S. Sambucini, M. Bottomley, Lo Surdo, A. Carfi
Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation M. Fukuoka, H. Daitoku, M. Hatta, H. Matsuzaki, S. Umemura, A. Fukamizu
Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer J. Shi, Y. Wang, L. Zeng, Y. Wu, J. Deng, Q. Zhang, Y. Lin, J. Li, T. Kang, M. Tao
Novel Histone Deacetylase Class IIa Selective Substrate Radiotracers for PET Imaging of Epigenetic Regulation in the Brain R. Bonomi, U. Mukhopadhyay, A. Shavrin, H. Yeh, A. Majhi, S. Dewage, A. Najjar, X. Lu, G. Cisneros, W. Tong
Redox regulation of FoxO transcription factors L.-O. Klotz, C. Sánchez-Ramos, I. Prieto-Arroyo, P. Urbánek, H. Steinbrenner, M. Monsalve