GCE Publications

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2022 Impact of queuosine modification of endogenous tRNAs on sense codon reassignment. Jillyn Tittle, David Schwark, Wil Biddle, Margaret Schmitt, John Fisk
2022 Polymer selection impacts the pharmaceutical profile of site-specifically conjugated Interferon-α2a. Niklas Hauptstein, Paria Pouyan, Kevin Wittwer, Gizem Cinar, Oliver Scherf-Clavel, Martina Raschig, Kai Licha, Tessa Lühmann, Ivo Nischang, Ulrich Schubert, Christian Pfaller, Rainer Haag, Lorenz Meinel
2022 Trifluoroacetyl Lysine as a Bromodomain Binding Mimic of Lysine Acetylation. Gregory Miller, Megan Flynn, Jeffrey Tom, Aimin Song, Andrea Cochran
2022 Editorial: Chemical Biology Tools for Peptide and Protein Research. Yu-Hsuan Tsai, Hideo Iwaï, Klaus Pors
2022 Generation and Characterization of Site-Specifically Mono-Ubiquitylated p53. Alexandra Julier, Vanessa Radtke, Andreas Marx, Martin Scheffner
2022 Genetic code degeneracy is established by the decoding center of the ribosome. Shixin Ye, Jean Lehmann
2022 Rational incorporation of any unnatural amino acid into proteins by machine learning on existing experimental proofs. Haoran Zhang, Zhetao Zheng, Liangzhen Dong, Ningning Shi, Yuelin Yang, Hongmin Chen, Yuxuan Shen, Qing Xia
2022 The complete chloroplast genome of the medical plant Huperzia crispata from the Huperziaceae family: structure, comparative analysis, and phylogenetic relationships. Dengpan Yin, Bo Pang, Haibo Li, Qiao Liu, Yufeng Zhai, Nan Ma, Tongtong Chen, Hongjun Shen, Qiaojun Jia, Dekai Wang
2022 Generating Efficient Pyrrolysyl-tRNA Synthetases for Structurally Diverse Non-Canonical Amino Acids. Savanna Avila-Crump, Marcus Hemshorn, Chloe Jones, Lea Mbengi, Kyle Meyer, Joshua Griffis, Subhashis Jana, Grace Petrina, Vinayak Pagar V, Andrew Karplus, James Petersson, John Perona, Ryan Mehl, Richard Cooley
2022 Genetic Code Expansion and Bio-Orthogonal Labeling Reveal Intact HIV-1 Capsids inside the Nucleus. Leo James
2022 Generation of Photocaged Nanobodies for Intracellular Applications in an Animal Using Genetic Code Expansion and Computationally Guided Protein Engineering. Jack O'Shea, Angeliki Goutou, Jack Brydon, Cyrus Sethna, Christopher Wood, Sebastian Greiss
2022 The tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism. Haolin Zhang, Xuemei Gong, Qianqian Zhao, Takahito Mukai, Oscar Vargas-Rodriguez, Huiming Zhang, Yuxing Zhang, Paul Wassel, Kazuaki Amikura, Julie Maupin-Furlow, Yan Ren, Xun Xu, Yuri Wolf, Kira Makarova, Eugene Koonin V, Yue Shen, Dieter Söll, Xian Fu
2022 Uncover New Reactivity of Genetically Encoded Alkyl Bromide Non-Canonical Amino Acids. Xin Shu, Sana Asghar, Fan Yang, Shang-Tong Li, Haifan Wu, Bing Yang
2022 Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding. Kelsey Kean, Stefanie Baril, Kelsey Lamb, Sarah Dishman, Joseph Treacy, Kendall Houk, Eric Brustad, Lindsey James, Marcey Waters
2022 Recent Advances in Fluorescence Imaging by Genetically Encoded Non-canonical Amino Acids. Sanghee Lee, Jonghoon Kim, Minseob Koh
2022 Genetic Code Expansion: Another Solution to Codon Assignments. Kensaku Sakamoto
2022 Expanding the chemical diversity of M13 bacteriophage. Grace Allen, Ashley Grahn, Katerina Kourentzi, Richard Willson, Sean Waldrop, Jiantao Guo, Brian Kay
2022 Tuning the Properties of Protein-Based Polymers Using High-Performance Orthogonal Translation Systems for the Incorporation of Aromatic Non-Canonical Amino Acids. Osher Gueta, Ortal Sheinenzon, Rotem Azulay, Hadas Shalit, Daniela Strugach, Dagan Hadar, Sigal Gelkop, Anat Milo, Miriam Amiram
2022 Expanding the functionality of proteins with genetically encoded dibenzo[,][1,4,5]thiadiazepine: a photo-transducer for photo-click decoration. Qin Xiong, Tingting Zheng, Xin Shen, Baolin Li, Jielin Fu, Xiaohu Zhao, Chunxia Wang, Zhipeng Yu
2022 Directed Evolution Pipeline for the Improvement of Orthogonal Translation Machinery for Genetic Code Expansion at Sense Codons. Wil Biddle, David Schwark, Margaret Schmitt, John Fisk
2022 Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue. Yingzi Tan, Miao Wang, Yijun Chen
2022 Measuring Repeat-Associated Non-AUG (RAN) Translation. Shaopeng Wang, Shuying Sun
2022 Engineered bacterial host for genetic encoding of physiologically stable protein nitration. Nikolaj Koch, Tobias Baumann, Jessica Nickling, Anna Dziegielewski, Nediljko Budisa
2022 Cryptochrome 1 as a state variable of the circadian clockwork of the suprachiasmatic nucleus: Evidence from translational switching. David McManus, Lenka Polidarova, Nicola Smyllie, Andrew Patton, Johanna Chesham, Elizabeth Maywood, Jason Chin, Michael Hastings
2022 A Photo-Crosslinking Approach to Identify Class II SUMO-1 Binders. Kira Brüninghoff, Stephanie Wulff, Wolfgang Dörner, Ruth Geiss-Friedlander, Henning Mootz