GCE Publications

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Expanding and reprogramming the genetic code J. Chin
Genetically encoding thioacetyl-lysine as a non-deacetylatable analog of lysine acetylation in Escherichia coli S. Venkat, D. Nannapaneni, C. Gregory, Q. Gan, M. McIntosh, C. Fan
Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog D. Rogerson, A. Sachdeva, K. Wang, T. Haq, A. Kazlauskaite, S. Hancock, N. Huguenin-Dezot, M. Muqit, A. Fry, R. Bayliss
Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3 A. Measures, D. Hewings, N. Theodoulou, L. Jursins, K. Lewendon, L. Jennings, T. Rooney, T. Heightman, S. Conway
Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria X. Luo, G. Fu, R. Wang, X. Zhu, C. Zambaldo, R. Liu, T. Liu, X. Lyu, J. Du, W. Xuan
Histone recognition and large-scale structural analysis of the human bromodomain family P. Filippakopoulos, S. Picaud, M. Mangos, T. Keates, J. Lambert, D. Barsyte-Lovejoy, I. Felletar, R. Volkmer, S. Muller, T. Pawson
Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics I. Ali, R. Conrad, E. Verdin, M. Ott
Genetically Encoded Protein Phosphorylation in Mammalian Cells V. Beránek, C. Reinkemeier, M. Zhang, A. Liang, G. Kym, J. Chin
A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications E. Flynn, O. Huang, F. Poy, M. Oppikofer, S. Bellon, Y. Tang, A. Cochran
Lysine acetylation targets protein complexes and co-regulates major cellular functions C. Choudhary, C. Kumar, F. Gnad, M. Nielsen, M. Rehman, T. Walther, J. Olsen, M. Mann
Genetically encoding Nε-acetyllysine in recombinant proteins H. Neumann, S . Y. Peak-Chew, J. Chin
Development of activity-based probes for the protein deacylase Sirt1 C. Goetz, D. Sprague, B. Smith
The growing landscape of lysine acetylation links metabolism and cell signalling C. Choudhary, B. Weinert, Y. Nishida, E. Verdin, M. Mann
Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair S. Hancock, R. Uprety, A. Deiters, J. Chin
Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC C. Tallant, E. Valentini, O. Fedorov, L. Overvoorde, F. Ferguson, P. Filippakopoulos, D. Svergun, S. Knapp, A. Ciulli
Functions and mechanisms of non-histone protein acetylation T. Narita, B. Weinert, C. Choudhary
Expanding the genetic code of Mus musculus S. Han, A. Yang, S. Lee, H.-W. Lee, C. Park, H.-S. Park
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase A. Brunet, L. Sweeney, J. Sturgill, K. Chua, P. Greer, Y. Lin, H. Tran, S. Ross, R. Mostoslavsky, H . Y. Cohen
Targeting bromodomains: epigenetic readers of lysine acetylation P. Filippakopoulos, S. Knapp
A genetically encoded 19F NMR probe for lysine acetylation F. Zhang, Q. Zhou, G. Yang, L. An, F. Li, J. Wang
FOXO4 Is Acetylated upon Peroxide Stress and Deacetylated by the Longevity Protein hSir2SIRT1 A. van der Horst, L. Tertoolen, L. de Vries-Smits, R. Frye, R. Medema, B. Burgering
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer T. Fujisawa, P. Filippakopoulos
Sir2 Deacetylases Exhibit Nucleophilic Participation of Acetyl-Lysine in NAD+ Cleavage B. Smith, J. Denu