GCE Publications

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The growing landscape of lysine acetylation links metabolism and cell signalling C. Choudhary, B. Weinert, Y. Nishida, E. Verdin, M. Mann
Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair S. Hancock, R. Uprety, A. Deiters, J. Chin
Development of activity-based probes for the protein deacylase Sirt1 C. Goetz, D. Sprague, B. Smith
Functions and mechanisms of non-histone protein acetylation T. Narita, B. Weinert, C. Choudhary
Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair S. Hancock, R. Uprety, A. Deiters, J. Chin
Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC C. Tallant, E. Valentini, O. Fedorov, L. Overvoorde, F. Ferguson, P. Filippakopoulos, D. Svergun, S. Knapp, A. Ciulli
Targeting bromodomains: epigenetic readers of lysine acetylation P. Filippakopoulos, S. Knapp
Expanding the genetic code of Mus musculus S. Han, A. Yang, S. Lee, H.-W. Lee, C. Park, H.-S. Park
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase A. Brunet, L. Sweeney, J. Sturgill, K. Chua, P. Greer, Y. Lin, H. Tran, S. Ross, R. Mostoslavsky, H . Y. Cohen
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer T. Fujisawa, P. Filippakopoulos
A genetically encoded 19F NMR probe for lysine acetylation F. Zhang, Q. Zhou, G. Yang, L. An, F. Li, J. Wang
FOXO4 Is Acetylated upon Peroxide Stress and Deacetylated by the Longevity Protein hSir2SIRT1 A. van der Horst, L. Tertoolen, L. de Vries-Smits, R. Frye, R. Medema, B. Burgering
Bromodomains: a new target class for drug development A. Cochran, A. Conery, R. Sims
Sir2 Deacetylases Exhibit Nucleophilic Participation of Acetyl-Lysine in NAD+ Cleavage B. Smith, J. Denu
Regulation of FoxO activity by CBP/p300–mediated acetylation L. van der Heide, M. Smidt
A chemical toolbox for the study of bromodomains and epigenetic signaling Q. Wu, D. Heidenreich, S. Zhou, S. Ackloo, A. Krämer, K. Nakka, E. Lima-Fernandes, G. Deblois, S. Duan, R. Vellanki
Acetyl-lysine Analog Peptides as Mechanistic Probes of Protein Deacetylases B. Smith, J. Denu
Regulation of FoxO transcription factors by acetylation and protein–protein interactions H. Daitoku, J.-i. Sakamaki, A. Fukamizu
Target Structure–Based Discovery of Small Molecules that Block Human p53 and CREB Binding Protein Association null Sachchidanand, L. Resnick-Silverman, S. Yan, S. Mutjaba, W.-j. Liu, L. Zeng, J. Manfredi, M.–M. Zhou
Mechanism-Based Inhibition of Sir2 Deacetylases by Thioacetyl-Lysine Peptide B. Smith, J. Denu
Polyspecific pyrrolysyl-tRNA synthetases from directed evolution L.-T. Guo, Y.-S. Wang, A. Nakamura, D. Eiler, J. Kavran, M. Wong, L. Kiessling, T. Steitz, P. O’Donoghue, D. Söll
Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes J. Lamonica, W. Deng, S. Kadauke, A. Campbell, R. Gamsjaeger, H. Wang, Y. Cheng, A. Billin, R. Hardison, J. Mackay