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3-cyano-L-phenylalanine

3-cyano-L-phenylalanine

ncAA Foundational Publication Support

Wang, Yane-Shih, Xinqiang Fang, Hsueh-Ying Chen, Bo Wu, Zhiyong U Wang, Christian Hilty, and Wenshe R Liu. (2013) 2013. “Genetic Incorporation Of Twelve Meta-Substituted Phenylalanine Derivatives Using A Single Pyrrolysyl-Trna Synthetase Mutant.”. Acs Chemical Biology 8 (2): 405-15. doi:10.1021/cb300512r.
ncAA Utility
can be a useful IR probe
ncAA Source
Exogenous - Purchased
ncAA Availability
Can be purchased from https://www.thermofisher.com/order/catalog/product/H62517.03
RS/tRNA Pair Usage Information
incorporated at medium levels into sfGFP2TAG (7 mg/L) with fidelity in E coli grown with 2 mM ncAA in GMML media.

RS/tRNA Pair(s)

ncAA Synonyms
63999-80-4
2-amino-3-(3-cyanophenyl)propanoic Acid
3-Cyanophenylalanine
3-cyano-dl-phenylalanine
DL-3-Cyanophenylalanine
h-dl-phe(3-cn)-oh
MFCD00190859
D-3-Cyanophenylalanine
2-amino-3-(3-cyano-phenyl)-propionic acid
2-Amino-3-(3-cyanophenyl)propanoicacid
ChEBI ID
233130
ChEBI Link
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI%3A233130&conversationCont…
PubChem Link
https://pubchem.ncbi.nlm.nih.gov/compound/10559569