ncAA Structure (png, jpg, jpeg)
ncAA Foundational Publication Support
Nguyen, Duy P, Hrvoje Lusic, Heinz Neumann, Prashant B Kapadnis, Alexander Deiters, and Jason W Chin. (2009) 2009. “Genetic Encoding And Labeling Of Aliphatic Azides And Alkynes In Recombinant Proteins Via A Pyrrolysyl-Trna Synthetase/Trna(Cua) Pair And Click Chemistry.”. Journal Of The American Chemical Society 131 (25): 8720-1. doi:10.1021/ja900553w.
Meineke, Birthe, Johannes Heimgärtner, Jürgen Eirich, Michael Landreh, and Simon J Elsässer. (2020) 2020. “Site-Specific Incorporation Of Two Ncaas For Two-Color Bioorthogonal Labeling And Crosslinking Of Proteins On Live Mammalian Cells.”. Cell Reports 31 (12): 107811. doi:10.1016/j.celrep.2020.107811.
ncAA Utility
Reactive handle for azide-alkyne cycloaddition
ncAA Source
Exogenous - Synthesized
ncAA Availability
n/a
RS/tRNA Pair Usage Information
First foundational paper shows installation by WT MbPylRS and second foundational paper shows installation by WT M mazeii PylRS.
ncAA Synonyms
(2S)-2-amino-6-{[(2-azidoethoxy)carbonyl]amino}hexanoic acid
1167421-25-1
(S)-2-Amino-6-(((2-azidoethoxy)carbonyl)amino)hexanoic acid
N?-2-Azidoethyloxycarbonyl-L-lysine
N6-[(2-Azidoethoxy)carbonyl]-L-lysine; (2S)-2-Amino-6-[[(2-azidoethoxy)carbonyl]amino]hexanoic Acid;(S)-2-Amino-6-[(2-azidoethoxy)carbonylamino]hexanoic Acid;N6-[(2-Azidoethoxy)carbonyl]-L-lysine;
SCHEMBL15546760
AKOS030212928
N6-((2-azidoethoxy)carbonyl)-L-lysine
NEpsilon-2-Azidoethyloxycarbonyl-L-lysine
AzeoK
1167421-25-1
(S)-2-Amino-6-(((2-azidoethoxy)carbonyl)amino)hexanoic acid
N?-2-Azidoethyloxycarbonyl-L-lysine
N6-[(2-Azidoethoxy)carbonyl]-L-lysine; (2S)-2-Amino-6-[[(2-azidoethoxy)carbonyl]amino]hexanoic Acid;(S)-2-Amino-6-[(2-azidoethoxy)carbonylamino]hexanoic Acid;N6-[(2-Azidoethoxy)carbonyl]-L-lysine;
SCHEMBL15546760
AKOS030212928
N6-((2-azidoethoxy)carbonyl)-L-lysine
NEpsilon-2-Azidoethyloxycarbonyl-L-lysine
AzeoK
ChEBI ID
233053
PubChem Link