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p-benzoyl-l-phenylalanine

Image showing the ChemDraw Structure of p-benzoyl-l-phenylalanine

ncAA Foundational Publication Support

Chin, Jason W., Andrew B. Martin, David S. King, Lei Wang, and Peter G. Schultz. (aug) 2002. “Addition Of A Photocrosslinking Amino Acid To The Genetic Code Of Escherichia Coli”. Proceedings Of The National Academy Of Sciences 99: 11020-11024. doi:10.1073/pnas.172226299.

ncAA Usage Publications

Nelson, Brock, Nathan Soper, and Tania J. Lupoli. (oct) 2023. “Bacterial J-Domains With C-Terminal Tags Contact The Substrate Binding Domain Of Dnak And Sequester Chaperone Activity”. Chembiochem: A European Journal Of Chemical Biology 24: e202300261. doi:10.1002/cbic.202300261.
Tholen, Marrit M. E., Bas J. H. M. Rosier, Robin T. Vermathen, Céline A. N. Sewnath, Cornelis Storm, Laura Woythe, Cristina Izquierdo-Lozano, et al. (jun) 2023. “Mapping Antibody Domain Exposure On Nanoparticle Surfaces Using Dna-Paint”. Acs Nano 17: 11665-11678. doi:10.1021/acsnano.3c02195.
Blueggel, Mike, Alexander Kroening, Matthias Kracht, Johannes van den Boom, Matthias Dabisch, Anna Goehring, Farnusch Kaschani, et al. (jun) 2023. “The Ubx Domain In Ubxd1 Organizes Ubiquitin Binding At The C-Terminus Of The Vcp/P97 Aaa-Atpase”. Nature Communications 14: 3258. doi:10.1038/s41467-023-38604-4.
van den Boom, Johannes, Guendalina Marini, Hemmo Meyer, and Helen R. Saibil. (jul) 2023. “Structural Basis Of Ubiquitin-Independent Pp1 Complex Disassembly By P97”. The Embo Journal 42: e113110. doi:10.15252/embj.2022113110.
van Aalen, Eva A., Bas J. H. M. Rosier, Tom Jansen, Simone F. A. Wouters, Robin T. Vermathen, Harmen J. van der Veer, José Yeste Lozano, et al. (jun) 2023. “Integrated Bioluminescent Immunoassays For High-Throughput Sampling And Continuous Monitoring Of Cytokines”. Analytical Chemistry 95: 8922-8931. doi:10.1021/acs.analchem.3c00745.
ncAA Utility
Used as a photocrosslinker, allowing for crosslinking and bioorthogonal ligation of protein.
ncAA Source
Exogenous - Purchased
ncAA Availability
Can be purchased from https://www.fishersci.com/shop/products/4-benzoyl-l-phenylalanine-95-thermo-scientific/AAH52083MD

RS/tRNA Pair(s)

ncAA Synonyms
L-4-Benzoylphenylalanine
4-benzoyl-l-phenylalanine
(S)-2-Amino-3-(4-benzoylphenyl)propanoic acid
Para-(Benzoyl)-Phenylalanine
p-benzoyl-l-phenylalanine
4-benzoylphenylalanine
L-Phenylalanine, 4-benzoyl-
L-p-Benzoylphenylalanine
ChEBI ID
44718
ChEBI Link
https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI%3A44718
PubChem Link
https://pubchem.ncbi.nlm.nih.gov/compound/4-Benzoyl-l-phenylalanine
ncAA Additional Notes
N/A