ncAA Structure (png, jpg, jpeg)
ncAA Foundational Publication Support
Wang, Yane-Shih, Xinqiang Fang, Hsueh-Ying Chen, Bo Wu, Zhiyong U Wang, Christian Hilty, and Wenshe R Liu. (2013) 2013. “Genetic Incorporation Of Twelve Meta-Substituted Phenylalanine Derivatives Using A Single Pyrrolysyl-Trna Synthetase Mutant.”. Acs Chemical Biology 8 (2): 405-15. doi:10.1021/cb300512r.
Zhang, Zhiwen, Brian A C Smith, Lei Wang, Ansgar Brock, Charles Cho, and Peter G Schultz. (2003) 2003. “A New Strategy For The Site-Specific Modification Of Proteins In Vivo.”. Biochemistry 42 (22): 6735-46.
ncAA Utility
can be used for protein ligation
ncAA Source
Exogenous - Synthesized
ncAA Availability
n/a
RS/tRNA Pair Usage Information
with the PylRS, it is incorporated at high levels into sfGFP2TAG (37 mg/L) with fidelity in E coli grown with 2 mM ncAA in GMML media.
ncAA Synonyms
3-(3-Acetylphenyl)-2-aminopropanoic acid
ChEBI ID
233949
PubChem Link