3-acetyl-L-phenylalanine

ncAA Structure (png, jpg, jpeg)
3-acetyl-L-phenylalanine

ncAA Foundational Publication Support

Wang, Yane-Shih, Xinqiang Fang, Hsueh-Ying Chen, Bo Wu, Zhiyong U Wang, Christian Hilty, and Wenshe R Liu. (2013) 2013. ā€œGenetic Incorporation of Twelve Meta-Substituted Phenylalanine Derivatives Using a Single Pyrrolysyl-TRNA Synthetase Mutantā€. ACS Chemical Biology 8 (2): 405-15. doi:10.1021/cb300512r.

Zhang, Zhiwen, Brian A C Smith, Lei Wang, Ansgar Brock, Charles Cho, and Peter G Schultz. (2003) 2003. ā€œA New Strategy for the Site-Specific Modification of Proteins in Vivoā€. Biochemistry 42 (22): 6735-46.

ncAA Utility
can be used for protein ligation
ncAA Source
Exogenous - Synthesized
ncAA Availability
n/a

RS/tRNA Pair Usage Information
with the PylRS, it is incorporated at high levels into sfGFP2TAG (37 mg/L) with fidelity in E coli grown with 2 mM ncAA in GMML media.

RS/tRNA Pair(s)


ncAA Synonyms
3-(3-Acetylphenyl)-2-aminopropanoic acid
ChEBI ID
233949