ncAA Structure (png, jpg, jpeg)
ncAA Foundational Publication Support
Liu, Chang C, and Peter G Schultz. (2006) 2006. “Recombinant Expression Of Selectively Sulfated Proteins In Escherichia Coli.”. Nature Biotechnology 24 (11): 1436-40.
ncAA Usage Publications
Parrish, Angela R, Xingyu She, Zheng Xiang, Irene Coin, Zhouxin Shen, Steven P Briggs, Andrew Dillin, and Lei Wang. (2012) 2012. “Expanding The Genetic Code Of Caenorhabditis Elegans Using Bacterial Aminoacyl-Trna Synthetase/Trna Pairs.”. Acs Chemical Biology 7 (7): 1292-302. doi:10.1021/cb200542j.
ncAA Utility
Labelling of muscles (global)
Dipeptide (DanAla-‐Ala) required for uptake and bioavailability
Dipeptide (DanAla-‐Ala) required for uptake and bioavailability
ncAA Source
Exogenous - Synthesized
ncAA Availability
N/A
RS/tRNA Pair Usage Information
Naturally occurs in eukaryotic systems as a post-translational modification for secreted proteins
ncAA Synonyms
sulfoTyr
sY
sY
ChEBI ID
232819
PubChem Link
ncAA Additional Notes
Uptake by cells can be poor due to negative charge.