GCE Publications

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2024 Generation of site-specifically labelled fluorescent human XPA to investigate DNA binding dynamics during nucleotide excision repair. Sahiti Kuppa, Elliot Corless, Colleen Caldwell, Maria Spies, Edwin Antony
2024 Electrochemical labelling of hydroxyindoles with chemoselectivity for site-specific protein bioconjugation. Conor Loynd, Soumya Roy, Vincent Ovalle, Sarah Canarelli, Atanu Mondal, Delilah Jewel, Elise Ficaretta, Eranthie Weerapana, Abhishek Chatterjee
2024 Directed Evolution of a Bacterial Leucyl tRNA in Mammalian Cells for Enhanced Noncanonical Amino Acid Mutagenesis. Rachel Huang, Delilah Jewel, Rachel Kelemen, Quan Pham, Tarah Yared, Shu Wang, Soumya Roy, Zeyi Huang, Samantha Levinson, Bharathi Sundaresh, Suyen Miranda, Tim van Opijnen, Abhishek Chatterjee
2024 Secondary Amine Catalysis in Enzyme Design: Broadening Protein Template Diversity through Genetic Code Expansion. Thomas Williams, Irshad Taily, Lewis Hatton, Andrey Berezin, Yi-Lin Wu, Vicent Moliner, Katarzyna Świderek, Yu-Hsuan Tsai, Louis Luk
2024 Orthogonal Translation for Site-Specific Installation of Post-translational Modifications. Qinglei Gan, Chenguang Fan
2024 An efficient pyrrolysyl-tRNA synthetase for economical production of MeHis-containing enzymes. Amy Hutton, Jake Foster, James Sanders, Christopher Taylor, Stefan Hoffmann, Yizhi Cai, Sarah Lovelock, Anthony Green
2024 Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion. Maria Weyh, Marie-Lena Jokisch, Tuan-Anh Nguyen, Maximilian Fottner, Kathrin Lang
2024 Non-canonical amino acids uncover the significant impact of Tyr671 on Taq DNA polymerase catalytic activity. Wanyi Chen, Binbin Chen, Xinjia Li, Gang Xu, Lirong Yang, Jianping Wu, Haoran Yu
2024 Genetically Encoded Photocaged Proteinogenic and Non-Proteinogenic Amino Acids. Xiaochen Yang, Xun-Cheng Su, Weimin Xuan
2024 Insights into the dynamics of the Ca2+ release-activated Ca2+ channel pore-forming complex Orai1. Maximilian Fröhlich, Julia Söllner, Isabella Derler
2024 Pinpointing Acidic Residues in Proteins. Weimin Xuan, Jun-An Ma
2024 Complete Chloroplast Genome of : Comparative and Phylogenetic Analysis. Peng Wei, Youzheng Li, Mei Ke, Yurong Hou, Abudureyimu Aikebaier, Zinian Wu
2024 Reversing the charge of lysine by genetic code expansion. Daniela Danková, Christian Olsen
2024 tRNA engineering strategies for genetic code expansion. YouJin Kim, Suho Cho, Joo-Chan Kim, Hee-Sung Park
2024 Tracking endogenous proteins based on RNA editing-mediated genetic code expansion. Min Hao, Xinyu Ling, Yi Sun, Xue Wang, Wenzhe Li, Liying Chang, Zhiying Zeng, Xiaomeng Shi, Mengxiao Niu, Liangyi Chen, Tao Liu
2024 PCNA as Protein-Based Nanoruler for Sub-10 nm Fluorescence Imaging. Dominic Helmerich, Made Budiarta, Danush Taban, Sören Doose, Gerti Beliu, Markus Sauer
2024 Two rare autosomal recessive neurological disorders identified by combined genetic approaches in a single consanguineous family with multiple offspring. Seda Susgun, Emrah Yucesan, Beyza Goncu, Sevde Sayin, Umit Kina, Cemil Ozgul, Omer Duzenli, Ozcan Kocaturk, Mustafa Calik, Ugur Ozbek, Sibel Iseri
2024 Suppressor tRNAs at the interface of genetic code expansion and medicine. Aya Awawdeh, Alexander Radecki, Oscar Vargas-Rodriguez
2024 Unnatural Amino Acid-Based Ionic Liquid Enables Oral Treatment of Nonsense Mutation Disease in Mice. Yujie Shi, Ningning Shi, Yuelin Yang, Zhetao Zheng, Qing Xia
2024 Characterizing lysine acetylation of glucokinase. Nour Fatema, Xinyu Li, Qinglei Gan, Chenguang Fan
2024 Development of orthogonal aminoacyl-tRNA synthetase mutant for incorporating a non-canonical amino acid. Dongheon Lee, Ja Kim, Tae Kim, Jong-Il Choi
2024 Disrupted protein interaction dynamics in a genetic neurodevelopmental disorder revealed by structural bioinformatics and genetic code expansion. Valerio Marino, Wanchana Phromkrasae, Michele Bertacchi, Paul Cassini, Krittalak Chakrabandhu, Daniele Dell'Orco, Michèle Studer
2024 Enhanced Directed Evolution in Mammalian Cells Yields a Hyperefficient Pyrrolysyl tRNA for Noncanonical Amino Acid Mutagenesis. Delilah Jewel, Rachel Kelemen, Rachel Huang, Zeyu Zhu, Bharathi Sundaresh, Kaitlin Malley, Quan Pham, Conor Loynd, Zeyi Huang, Tim van Opijnen, Abhishek Chatterjee
2024 Matrix Metalloproteinase-Responsive Delivery of PEGylated Fibroblast Growth Factor 2. Marcus Gutmann, Debora Reinhardt, Christian Seidensticker, Martina Raschig, Lukas Hahn, Alessandra Moscaroli, Martin Behe, Lorenz Meinel, Tessa Lühmann
2024 Affinity-Directed Site-Specific Protein Labeling and Its Application to Antibody-Drug Conjugates. Sooin Kim, Sanggil Kim, Sangji Kim, Namkyoung Kim, Sang Lee, Hanbin Yi, Seungeun Lee, Taebo Sim, Yongseok Kwon, Hyun Lee