ncAA Structure (png, jpg, jpeg)
ncAA Foundational Publication Support
Young, Douglas D, Travis S Young, Michael Jahnz, Insha Ahmad, Glen Spraggon, and Peter G Schultz. (2011) 2011. “An Evolved Aminoacyl-Trna Synthetase With Atypical Polysubstrate Specificity.”. Biochemistry 50 (11): 1894-900. doi:10.1021/bi101929e.
Wang, Yane-Shih, Xinqiang Fang, Ashley L Wallace, Bo Wu, and Wenshe R Liu. (2012) 2012. “A Rationally Designed Pyrrolysyl-Trna Synthetase Mutant With A Broad Substrate Spectrum.”. Journal Of The American Chemical Society 134 (6): 2950-3. doi:10.1021/ja211972x.
ncAA Utility
Reactive handle for azide-alkyne cycloaddition
ncAA Source
Exogenous - Synthesized
ncAA Availability
n/a
RS/tRNA Pair Usage Information
incorporated at medium levels (8 mg/L) with fidelity in E coli grown with 2 mM ncAA in GMML media
ChEBI ID
232455