DiZHSeC

ncAA Structure (png, jpg, jpeg)
dizhsec

ncAA Foundational Publication Support

Yang, Yi, Haiping Song, Dan He, Shuai Zhang, Shizhong Dai, Shixian Li, Rong Meng, Chu Wang, and Peng Chen. (2017) 2016. ā€œGenetically Encoded Protein Photocrosslinker With a Transferable Mass Spectrometry-Identifiable Labelā€. Nature Communications. doi:https://doi.org/10.1038/ncomms12299.

ncAA Protocols

Ye, Yang, Haiping Song, and Dan He. (2017) 2017. ā€œGenetically Encoded Releasable Photo-Cross-Linking Strategies for Studying Protein–protein Interactions in Living Cellsā€. Nature Communications. doi:https://doi.org/10.1038/nprot.2017.090.

ncAA Utility
photo-affinity crosslinker with a built-in, transferable mass spectrometry label.
ncAA Source
Exogenous - Synthesized
ncAA Availability
Synthesized in paper

RS/tRNA Pair Usage Information
Used with DZKRS, which is the same RS/tRNA pair as for DiZPK. Used in E. coli at 330 μM concentration and mammalian at 1 mM concentration.

RS/tRNA Pair(s)


ncAA Synonyms
DiZHSeC
2230724-46-4
(S)-2-amino-4-((3-((3-(3-methyl-3H-diazirin-3-yl)propyl)amino)-3-oxopropyl)selanyl)butanoic acid
orb2566402
HY-D1032
DS-019198
CS-0030119
(2S)-2-amino-4-[3-[3-(3-methyldiazirin-3-yl)propylamino]-3-oxopropyl]selanylbutanoic acid
ChEBI ID
747357