Nε-(tert-Butoxycarbonyl)-L-lysine (BocLys)

BocLys

ncAA Foundational Publication Support

Yanagisawa, Tatsuo, Ryohei Ishii, Ryuya Fukunaga, Takatsugu Kobayashi, Kensaku Sakamoto, and Shigeyuki Yokoyama. (2008) 2008. “Multistep Engineering of Pyrrolysyl-TRNA Synthetase to Genetically Encode N(epsilon)-(o-Azidobenzyloxycarbonyl) Lysine for Site-Specific Protein Modification”. Chemistry & Biology 15 (11): 1187-97. doi:10.1016/j.chembiol.2008.10.004.

ncAA Usage Publications

Greiss, Sebastian, and Jason W Chin. (2011) 2011. “Expanding the Genetic Code of an Animal”. Journal of the American Chemical Society 133 (36): 14196-9. doi:10.1021/ja2054034.

ncAA Utility

Extra-‐chromosomal array (low stability), biolistic bombardment. Scattered in different places in animal.

ncAA Source

Exogenous - Purchased

ncAA Availability

Can be purchased from https://www.sigmaaldrich.com/US/en/product/aldrich/359688

RS/tRNA Pair(s)

Nε-(tert-Butoxycarbonyl)-L-lysine (BocLys) RS 1

RS/tRNA Pair Development Year

2011

RS Organism of Origin

Methanosarcina mazei

BCNRS

RS/tRNA Pair Development Year

2012

RS Organism of Origin

Methanosarcina barkeri

TCORS

RS/tRNA Pair Development Year

2012

RS Organism of Origin

Methanosarcina barkeri

ncAA Synonyms

H-Lys(Boc)-OH
2418-95-3
N6-(tert-butoxycarbonyl)-L-lysine
Lys(Boc)
Nepsilon-Boc-L-lysine

ChEBI ID

233034

ChEBI Link

https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI%3A233034&conversationCont…

PubChem Link

https://pubchem.ncbi.nlm.nih.gov/compound/Boc-Lys-OH