GCE Publications

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2024 Engineering of cell-surface receptors for analysis of receptor internalization and detection of receptor-specific glycosylation. Chang-Hee Lee, Sookil Park, Sanggil Kim, Ji Hyun, Hyun Lee, Injae Shin
2024 Genetic Encoding of Phosphorylated Amino Acids into Proteins. Michael Allen, Andrew Karplus, Ryan Mehl, Richard Cooley
2024 Directed evolution of the fluorescent protein CGP with biosynthesized noncanonical amino acids. Yanhong Yang, Jing Zhang, Jian Yang, Huiwen Luo, Yingjie Sun, Famin Ke, Qin Wang, Xiaowei Gao
2024 Light-Activatable MBD-Readers of 5-Methylcytosine Reveal Domain-Dependent Chromatin Association Kinetics In Vivo. Tzu-Chen Lin, Lena Engelhard, Benedikt Söldner, Rasmus Linser, Daniel Summerer
2024 Diversification of Phage-Displayed Peptide Libraries with Noncanonical Amino Acid Mutagenesis and Chemical Modification. Trae Hampton, Wenshe Liu
2024 Practical Approaches to Genetic Code Expansion with Aminoacyl-tRNA Synthetase/tRNA Pairs. Anton Perdiguero, Alexandria Liang
2024 Self-assembly of temperature-responsive di-block polypeptides functionalized with unnatural amino acids. Rotem Azulay, Daniela Strugach, Miriam Amiram
2023 Site-Specific Introduction of Bioorthogonal Handles to Nanopores by Genetic Code Expansion. Jing Yang, Kefan Wang, Shanyu Zhang, Xiaocui Zheng, Tongxiao Cui, Xian Yang, Yao Liu, Di Lu, Yuqin Wang, Xiao Tian, Panke Zhang, Shuo Huang, Ran Xie
2023 Biosynthesis and Genetic Encoding of Non-hydrolyzable Phosphoserine into Recombinant Proteins in Escherichia coli. Phillip Zhu, Ryan Mehl, Richard Cooley
2023 The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase Mike Blueggel, Alexander Kroening, Matthias Kracht, Johannes van den Boom, Matthias Dabisch, Anna Goehring, Farnusch Kaschani, Markus Kaiser, Peter Bayer, Hemmo Meyer, Christine Beuck
2023 An evolved pyrrolysyl-tRNA synthetase with polysubstrate specificity expands the toolbox for engineering enzymes with incorporation of noncanonical amino acids. Ke Liu, Ling Jiang, Shuang Ma, Zhongdi Song, Lun Wang, Qunfeng Zhang, Renhao Xu, Lirong Yang, Jianping Wu, Haoran Yu
2023 Non-canonical amino acid incorporation into AAV5 capsid enhances lung transduction in mice. Hao Chang, Ailing Du, Jun Jiang, Lingzhi Ren, Nan Liu, Xuntao Zhou, Jialing Liang, Guangping Gao, Dan Wang
2023 Genetic Encoding of Arylazopyrazole Phenylalanine for Optical Control of Translation. Chasity Janosko, Olivia Shade, Taylor Courtney, Trevor Horst, Melinda Liu, Sagar Khare, Alexander Deiters
2023 Selective Inhibition of Kinase Activity in Mammalian Cells by Bioorthogonal Ligand Tethering. Jinghao Chen, Yang Huang, Wen-Biao Gan, Yu-Hsuan Tsai
2023 Shedding light on ORAI1 channel with genetic code expansion. Sher Ali, Guolin Ma, Yubin Zhou
2023 Residue selective crosslinking of proteins through photoactivatable or proximity-enabled reactivity. Jun Liu, Bing Yang, Lei Wang
2023 Genetic encoding of 3-nitro-tyrosine reveals the impacts of 14-3-3 nitration on client binding and dephosphorylation. Phillip Zhu, Kyle Nguyen, Aidan Estelle, Nikolai Sluchanko, Ryan Mehl, Richard Cooley
2023 Structural basis of ubiquitin-independent PP1 complex disassembly by p97 Johannes van den Boom, Guendalina Marini, Hemmo Meyer, Helen Saibil
2023 Use of non-canonical amino acids in genetic code expansion-based therapeutics: Effects on mouse gut microbiota. Manyu Liang, Yanhong Yang, Jing Zhang, Yingjie Sun, Haixia Peng, Huawei Yi, Qin Wang, Xiaowei Gao
2023 Redesigning methionyl-tRNA synthetase for β-methionine activity with adaptive landscape flattening and experiments. Vaitea Opuu, Giuliano Nigro, Christine Lazennec-Schurdevin, Yves Mechulam, Emmanuelle Schmitt, Thomas Simonson
2023 Conformational GPCR BRET Sensors Based on Bioorthogonal Labeling of Noncanonical Amino Acids. Maria Kowalski-Jahn, Hannes Schihada, Gunnar Schulte
2023 Controlled Genetic Encoding of Unnatural Amino Acids in a Protein Nanopore. Xue-Yuan Wu, Meng-Yin Li, Shao-Jun Yang, Jie Jiang, Yi-Lun Ying, Peng Chen, Yi-Tao Long
2023 An intact amber-free HIV-1 system for in-virus protein bioorthogonal click labeling that delineates envelope conformational dynamics. Yuanyun Ao, Jonathan Grover, Yang Han, Guohua Zhong, Wenyi Qin, Dibya Ghimire, Anzarul Haque, Rajanya Bhattacharjee, Baoshan Zhang, James Arthos, Edward Lemke, Peter Kwong, Maolin Lu
2023 Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and suppresses autoimmunity. Bo Zhang, Jiaqi Sun, Yeshuang Yuan, Dezhong Ji, Yeting Sun, Yudong Liu, Shengjie Li, Xingxing Zhu, Xunyao Wu, Jin Hu, Qiu Xie, Ling Wu, Lulu Liu, Boyang Cheng, Yuanjie Zhang, Lingjuan Jiang, Lidan Zhao, Fei Yu, Wei Song, Min Wang, Yue Xu, Shiliang Ma, Yunyun Fei, Lihe Zhang, Demin Zhou, Xuan Zhang
2023 Archeal tRNA meets biotechnology: From vaccines to genetic code expansion. Lluís de Pouplana