GCE Publications

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2023 Customized synthesis of phosphoprotein bearing phosphoserine or its nonhydrolyzable analog. Dong Liu, Yingying Liu, Hua-Zhen Duan, Xinjie Chen, Yanan Wang, Ting Wang, Qing Yu, Yong-Xiang Chen, Yuan Lu
2023 Mapping Antibody Domain Exposure on Nanoparticle Surfaces Using DNA-PAINT Marrit Tholen, Bas Rosier, Robin Vermathen, Céline Sewnath, Cornelis Storm, Laura Woythe, Cristina Izquierdo-Lozano, Roger Riera, Marjolein van Egmond, Maarten Merkx, Lorenzo Albertazzi
2023 Attenuating RNA Viruses with Expanded Genetic Codes to Evoke Adjustable Immune Response in PylRS-tRNACUAPyl Transgenic Mice. Zhetao Zheng, Xuesheng Wu, Yu Wang, Xu Yang, Hongmin Chen, Yuxuan Shen, Yuelin Yang, Qing Xia
2023 Combining non-canonical amino acid mutagenesis and native chemical ligation for multiply modifying proteins: A case study of α-synuclein post-translational modifications. Ana Galesic, Buyan Pan, Jennifer Ramirez, Elizabeth Rhoades, Matthew Pratt, James Petersson
2023 Site-Specific Incorporation of Sulfotyrosine into Proteins in Mammalian Cells. Xinyuan He, Yan Chen, Jiantao Guo, Wei Niu
2023 Genetic code expansion in E. coli enables production of a functional 'ready-to-click' T cell receptor-specific scFv. Rajeev Pasupuleti, Francesca Rosato, Dajana Kolanovic, Olga Makshakova, Winfried Römer, Birgit Wiltschi
2023 Employing non-canonical amino acids towards the immobilization of a hyperthermophilic enzyme to increase protein stability. Hannah Switzer, Christina Howard, John Halonski, Emily Peairs, Nolan Smith, Maddy Zamecnik, Sanjana Verma, Douglas Young
2023 Studying Reversible Protein Post-translational Modification through Co-translational Modification. Dan Wu, Tao Liu
2023 Evaluation of acyllysine isostere interactions with the aromatic pocket of the AF9 YEATS domain. Christopher Travis, Denver Francis, David Williams, Marcey Waters
2023 Site-Specific Introduction of Bioorthogonal Handles to Nanopores by Genetic Code Expansion. Jing Yang, Kefan Wang, Shanyu Zhang, Xiaocui Zheng, Tongxiao Cui, Xian Yang, Yao Liu, Di Lu, Yuqin Wang, Xiao Tian, Panke Zhang, Shuo Huang, Ran Xie
2023 Biosynthesis and Genetic Encoding of Non-hydrolyzable Phosphoserine into Recombinant Proteins in Escherichia coli. Phillip Zhu, Ryan Mehl, Richard Cooley
2023 The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase Mike Blueggel, Alexander Kroening, Matthias Kracht, Johannes van den Boom, Matthias Dabisch, Anna Goehring, Farnusch Kaschani, Markus Kaiser, Peter Bayer, Hemmo Meyer, Christine Beuck
2023 An evolved pyrrolysyl-tRNA synthetase with polysubstrate specificity expands the toolbox for engineering enzymes with incorporation of noncanonical amino acids. Ke Liu, Ling Jiang, Shuang Ma, Zhongdi Song, Lun Wang, Qunfeng Zhang, Renhao Xu, Lirong Yang, Jianping Wu, Haoran Yu
2023 Non-canonical amino acid incorporation into AAV5 capsid enhances lung transduction in mice. Hao Chang, Ailing Du, Jun Jiang, Lingzhi Ren, Nan Liu, Xuntao Zhou, Jialing Liang, Guangping Gao, Dan Wang
2023 Genetic Encoding of Arylazopyrazole Phenylalanine for Optical Control of Translation. Chasity Janosko, Olivia Shade, Taylor Courtney, Trevor Horst, Melinda Liu, Sagar Khare, Alexander Deiters
2023 Selective Inhibition of Kinase Activity in Mammalian Cells by Bioorthogonal Ligand Tethering. Jinghao Chen, Yang Huang, Wen-Biao Gan, Yu-Hsuan Tsai
2023 Shedding light on ORAI1 channel with genetic code expansion. Sher Ali, Guolin Ma, Yubin Zhou
2023 Residue selective crosslinking of proteins through photoactivatable or proximity-enabled reactivity. Jun Liu, Bing Yang, Lei Wang
2023 Genetic encoding of 3-nitro-tyrosine reveals the impacts of 14-3-3 nitration on client binding and dephosphorylation. Phillip Zhu, Kyle Nguyen, Aidan Estelle, Nikolai Sluchanko, Ryan Mehl, Richard Cooley
2023 Autoregulation of GPCR signalling through the third intracellular loop. Fredrik Sadler, Ning Ma, Michael Ritt, Yatharth Sharma, Nagarajan Vaidehi, Sivaraj Sivaramakrishnan
2023 Structural basis of ubiquitin-independent PP1 complex disassembly by p97 Johannes van den Boom, Guendalina Marini, Hemmo Meyer, Helen Saibil
2023 Use of non-canonical amino acids in genetic code expansion-based therapeutics: Effects on mouse gut microbiota. Manyu Liang, Yanhong Yang, Jing Zhang, Yingjie Sun, Haixia Peng, Huawei Yi, Qin Wang, Xiaowei Gao
2023 Redesigning methionyl-tRNA synthetase for β-methionine activity with adaptive landscape flattening and experiments. Vaitea Opuu, Giuliano Nigro, Christine Lazennec-Schurdevin, Yves Mechulam, Emmanuelle Schmitt, Thomas Simonson
2023 Conformational GPCR BRET Sensors Based on Bioorthogonal Labeling of Noncanonical Amino Acids. Maria Kowalski-Jahn, Hannes Schihada, Gunnar Schulte
2023 Controlled Genetic Encoding of Unnatural Amino Acids in a Protein Nanopore. Xue-Yuan Wu, Meng-Yin Li, Shao-Jun Yang, Jie Jiang, Yi-Lun Ying, Peng Chen, Yi-Tao Long