GCE Publications

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2023 Use of non-canonical amino acids in genetic code expansion-based therapeutics: Effects on mouse gut microbiota. Manyu Liang, Yanhong Yang, Jing Zhang, Yingjie Sun, Haixia Peng, Huawei Yi, Qin Wang, Xiaowei Gao
2023 Redesigning methionyl-tRNA synthetase for β-methionine activity with adaptive landscape flattening and experiments. Vaitea Opuu, Giuliano Nigro, Christine Lazennec-Schurdevin, Yves Mechulam, Emmanuelle Schmitt, Thomas Simonson
2023 Conformational GPCR BRET Sensors Based on Bioorthogonal Labeling of Noncanonical Amino Acids. Maria Kowalski-Jahn, Hannes Schihada, Gunnar Schulte
2023 Controlled Genetic Encoding of Unnatural Amino Acids in a Protein Nanopore. Xue-Yuan Wu, Meng-Yin Li, Shao-Jun Yang, Jie Jiang, Yi-Lun Ying, Peng Chen, Yi-Tao Long
2023 An intact amber-free HIV-1 system for in-virus protein bioorthogonal click labeling that delineates envelope conformational dynamics. Yuanyun Ao, Jonathan Grover, Yang Han, Guohua Zhong, Wenyi Qin, Dibya Ghimire, Anzarul Haque, Rajanya Bhattacharjee, Baoshan Zhang, James Arthos, Edward Lemke, Peter Kwong, Maolin Lu
2023 Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and suppresses autoimmunity. Bo Zhang, Jiaqi Sun, Yeshuang Yuan, Dezhong Ji, Yeting Sun, Yudong Liu, Shengjie Li, Xingxing Zhu, Xunyao Wu, Jin Hu, Qiu Xie, Ling Wu, Lulu Liu, Boyang Cheng, Yuanjie Zhang, Lingjuan Jiang, Lidan Zhao, Fei Yu, Wei Song, Min Wang, Yue Xu, Shiliang Ma, Yunyun Fei, Lihe Zhang, Demin Zhou, Xuan Zhang
2023 Archeal tRNA meets biotechnology: From vaccines to genetic code expansion. Lluís de Pouplana
2023 Site-Specific Introduction of Bioorthogonal Handles to Nanopores by Genetic Code Expansion. Jing Yang, Kefan Wang, Shanyu Zhang, Xiaocui Zheng, Tongxiao Cui, Xian Yang, Yao Liu, Di Lu, Yuqin Wang, Xiao Tian, Panke Zhang, Shuo Huang, Ran Xie
2023 Integrated Bioluminescent Immunoassays for High-Throughput Sampling and Continuous Monitoring of Cytokines Eva van Aalen, Bas Rosier, Tom Jansen, Simone Wouters, Robin Vermathen, Harmen van der Veer, José Lozano, Sheeza Mughal, Juan Fernández-Costa, Javier Ramón-Azcón, Jaap Toonder, Maarten Merkx
2023 Near Infrared Light-Triggered Photocatalytic Decaging for Remote-Controlled Spatiotemporal Activation in Living Mice. Xuan Liang, Shan Qian, Zhizheng Lou, Renming Hu, Yuchen Hou, Peng Chen, Xinyuan Fan
2023 Redirecting the JAK-STAT signal blocks the SARS-CoV-2 replication. George Augustine, Valappil Sisila, Mohan Indhu, Divya Gupta, Dixit Tandel, Krishnan Harshan, Ganesh Shanmugam, Padmanabhan Padmapriya, Srinivasan Sivasubramanian, Krishnaswamy Kaveri, Kamini Ramudu, Niraikulam Ayyadurai
2023 Genetically Encoded 1,2-Aminothiol for Site-Specific Modification of a Cellular Membrane Protein via TAMM Condensation. Han Sun, Yang Huang, Yu-Hsuan Tsai
2023 Minimizing the Anticodon-Recognized Loop of Tyrosyl-tRNA Synthetase to Improve the Efficiency of Incorporating Noncanonical Amino Acids. Zhiyang Hu, Jinming Liang, Taogeng Su, Di Zhang, Hao Li, Xiangdong Gao, Wenbin Yao, Xiaoda Song
2023 An Efficient Opal-Suppressor Tryptophanyl Pair Creates New Routes for Simultaneously Incorporating up to Three Distinct Noncanonical Amino Acids into Proteins in Mammalian Cells. Arianna Osgood, Yunan Zheng, Soumya Roy, Nikolaos Biris, Myer Hussain, Conor Loynd, Delilah Jewel, James Italia, Abhishek Chatterjee
2023 Chemically Acylated tRNAs are Functional in Zebrafish Embryos. Wes Brown, Jason Galpin, Carolyn Rosenblum, Michael Tsang, Christopher Ahern, Alexander Deiters
2023 Human 14-3-3 Proteins Site-selectively Bind the Mutational Hotspot Region of SARS-CoV-2 Nucleoprotein Modulating its Phosphoregulation. Kristina Tugaeva V, Andrey Sysoev, Anna Kapitonova, Jake Smith, Phillip Zhu, Richard Cooley, Alfred Antson, Nikolai Sluchanko
2023 Enhancing the performance of a mutant pyrrolysyl-tRNA synthetase to create a highly versatile eukaryotic cell-free protein synthesis tool. Jeffrey Schloßhauer, Anne Zemella, Srujan Dondapati, Lena Thoring, Manpreet Meyer, Stefan Kubick
2023 Advances in Noncanonical Amino Acid Incorporation for Enzyme Engineering Applications. Sandro Giger, Rebecca Buller
2023 Applications of genetic code expansion and photosensitive UAAs in studying membrane proteins. Shu Zhao, Dong Liu
2023 Regulation of IL-24/IL-20R2 complex formation using photocaged tyrosines and UV light. Phuong Pham, Jiří Zahradník, Lucie Kolářová, Bohdan Schneider, Gustavo Fuertes
2023 Generation of Amber Suppression Cell Lines Using CRISPR-Cas9. Birthe Meineke, Simon Elsässer
2023 A platform for distributed production of synthetic nitrated proteins in live bacteria. Neil Butler, Sabyasachi Sen, Lucas Brown, Minwei Lin, Aditya Kunjapur
2023 Photocrosslinking-induced CRAC channel-like Orai1 activation independent of STIM1. Lena Maltan, Sarah Weiß, Hadil Najjar, Melanie Leopold, Sonja Lindinger, Carmen Höglinger, Lorenz Höbarth, Matthias Sallinger, Herwig Grabmayr, Sascha Berlansky, Denis Krivic, Valentina Hopl, Anna Blaimschein, Marc Fahrner, Irene Frischauf, Adéla Tiffner, Isabella Derler
2023 Engineering Small Molecule Switches of Protein Function in Zebrafish Embryos. Wes Brown, Joshua Wesalo, Michael Tsang, Alexander Deiters
2023 Building biomaterials through genetic code expansion. Valappil Sisila, Mohan Indhu, Janani Radhakrishnan, Niraikulam Ayyadurai