GCE Publications

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2023 Advances in Biosynthesis of Non-Canonical Amino Acids (ncAAs) and the Methods of ncAAs Incorporation into Proteins. Liang Chen, Xiulan Xin, Yuning Zhang, Shunyao Li, Xiaoman Zhao, Song Li, Zhaochu Xu
2023 Covalent Proteins as Targeted Radionuclide Therapies Enhance Antitumor Effects. Paul Klauser, Shalini Chopra, Li Cao, Kondapa Bobba, Bingchen Yu, Youngho Seo, Emily Chan, Robert Flavell, Michael Evans, Lei Wang
2023 Reprogramming Initiator and Nonsense Codons to Simultaneously Install Three Distinct Noncanonical Amino Acids into Proteins in E. coli. Han-Kai Jiang, Jeffery Tharp
2023 Bioorthogonal Tethering Enhances Drug Fragment Affinity for G Protein-Coupled Receptors in Live Cells. Jordan Mattheisen, Chris Limberakis, Roger Ruggeri, Matthew Dowling, Christopher Ende, Emilie Ceraudo, Thomas Huber, Christopher McClendon, Thomas Sakmar
2023 Linking chromatin acylation mark-defined proteome and genome in living cells. Fangfei Qin, Boyuan Li, Hui Wang, Sihui Ma, Jiaofeng Li, Shanglin Liu, Linghao Kong, Huangtao Zheng, Rongfeng Zhu, Yu Han, Mingdong Yang, Kai Li, Xiong Ji, Peng Chen
2023 7SK methylation by METTL3 promotes transcriptional activity Marcelo Perez-Pepe, Anthony Desotell, Hengyi Li, Wenxue Li, Bing Han, Qishan Lin, Daryl Klein, Yansheng Liu, Hani Goodarzi, Claudio Alarcón
2023 A New PETase from the Human Saliva Metagenome and Its Functional Modification via Genetic Code Expansion in Bacteria. Mirren White, Stephen Wallace
2023 Non-Canonical Amino Acids in Analyses of Protease Structure and Function. Peter Goettig, Nikolaj Koch, Nediljko Budisa
2023 Establishing the fundamental rules for genetic code expansion. Souvik Sinha, Mohd Ahsan, Giulia Palermo
2023 Protein Expression with Biosynthesized Noncanonical Amino Acids. Yong Wang, Wenkang Cai, Boyang Han, Tao Liu
2023 Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues. Christopher Taylor, Florence Hardy, Ashleigh Burke, Riley Bednar, Ryan Mehl, Anthony Green, Sarah Lovelock
2023 Capturing Covalent Catalytic Intermediates by Enzyme Mutants: Recent Advances in Methodologies and Applications. Yongchao Wang, Shan Tang
2023 Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family. Sören Kirchgäßner, Michael Braun, Natascha Bartlick, Cengiz Koç, Christopher Reinkemeier, Edward Lemke, Thilo Stehle, Dirk Schwarzer
2023 Engineering enzyme activity using an expanded amino acid alphabet. Zachary Birch-Price, Christopher Taylor, Mary Ortmayer, Anthony Green
2023 Synthetic Organelles for Multiple mRNA Selective Genetic Code Expansions in Eukaryotes. Christopher Reinkemeier, Edward Lemke
2022 Engineered bacterial host for genetic encoding of physiologically stable protein nitration. Nikolaj Koch, Tobias Baumann, Jessica Nickling, Anna Dziegielewski, Nediljko Budisa
2022 Cryptochrome 1 as a state variable of the circadian clockwork of the suprachiasmatic nucleus: Evidence from translational switching. David McManus, Lenka Polidarova, Nicola Smyllie, Andrew Patton, Johanna Chesham, Elizabeth Maywood, Jason Chin, Michael Hastings
2022 A Photo-Crosslinking Approach to Identify Class II SUMO-1 Binders. Kira Brüninghoff, Stephanie Wulff, Wolfgang Dörner, Ruth Geiss-Friedlander, Henning Mootz
2022 Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining. Maria Cabello-Lobato, Matthew Jenner, Metztli Cisneros-Aguirre, Kira Brüninghoff, Zac Sandy, Isabelle da Costa, Thomas Jowitt, Christian Loch, Stephen Jackson, Qian Wu, Henning Mootz, Jeremy Stark, Matthew Cliff, Christine Schmidt
2022 Selective Inhibition of Cysteine-Dependent Enzymes by Bioorthogonal Tethering. Luke Spear, Yang Huang, Jinghao Chen, Alexander Nödling, Satpal Virdee, Yu-Hsuan Tsai
2022 Genetically encoding latent bioreactive amino acids and the development of covalent protein drugs. Nanxi Wang, Lei Wang
2022 New covalent bonding ability for proteins. Li Cao, Lei Wang
2022 Applications of Genetic Code Expansion in Studying Protein Post-translational Modification. Jinghao Chen, Yu-Hsuan Tsai
2022 Measuring Repeat-Associated Non-AUG (RAN) Translation. Shaopeng Wang, Shuying Sun
2022 Minimal genetically encoded tags for fluorescent protein labeling in living neurons. Aleksandra Arsić, Cathleen Hagemann, Nevena Stajković, Timm Schubert, Ivana Nikić-Spiegel