pAcPhe RS (LW1-RS; pAcF-RS) RS/tRNA Pair Development Year 2003 ncAA(s) Incorporated p-acetyl-L-phenylalanine
pCNPhe RS1 (pCNF-RS; polyspecific RS) RS/tRNA Pair Development Year 2006 ncAA(s) Incorporated p-cyano-L-phenylalanine p-azido-L-phenylalanine (pAzF) p-iodo-L-phenylalanine p-bromo-L-phenylalanine p-acetyl-L-phenylalanine p-isopropyl-L-phenylalanine para-nitro-L-phenylalanine O-allyl-L-tyrosine p-ethynyl-L-phenylalanine BiphenylAla(BipAla) O-tert-butyl-L-tyrosine (Tby) O-propargyl-L-tyrosine p-chloro-L-phenylalanine p-fluoro-L-phenylalanine p-trifluoroacetyl-L-phenylalanine O-benzyl-L-serine
D9-nitroTyr-MaPylRS RS/tRNA Pair Development Year 2022 ncAA(s) Incorporated 3-nitro-L-tyrosine 3-iodo-L-tyrosine
3-nitroTyr(A7) RS/tRNA(CUA) RS/tRNA Pair Development Year 2020 ncAA(s) Incorporated 3-nitro-L-tyrosine
F4-nitroTyr-MbPylRS RS/tRNA Pair Development Year 2019 ncAA(s) Incorporated 3-nitro-L-phenylalanine 3-nitro-L-tyrosine
BpaRS-T158S,A31V RS/tRNA Pair Development Year 2009 ncAA(s) Incorporated 4-Fluoro-p-benzoyl-L-phenylalanine(4F-Bpa) Thyronine p-benzoyl-L-phenylalanine (Bpa)
BpaRS-V164A RS/tRNA Pair Development Year 2009 ncAA(s) Incorporated 3-Fluoro-4-nitro-p benzoyl-L phenylalanine 4-Nitro-p-benzoyl-L phenylalanine
EAziRS (improved version of EcAziRS or p-azidoPheRS-1) RS/tRNA Pair Development Year 2009 ncAA(s) Incorporated p-azido-L-phenylalanine (pAzF)
3-nitroTyr(5B) RS/tRNA(CUA) RS/tRNA Pair Development Year 2014 ncAA(s) Incorporated 3-nitro-L-tyrosine
Thr412Gly-cePheRS RS/tRNA Pair Development Year 2015 ncAA(s) Incorporated p-azido-L-phenylalanine (pAzF)
DZKRS RS/tRNA Pair Development Year 2011 ncAA(s) Incorporated (3-(3-Methyl-3H diazirine-3-yl)-propaminocarbonyl- Nε-L-lysine ( DiZPK)
pAcFRS.2.t1 RS/tRNA Pair Development Year 2015 ncAA(s) Incorporated p-acetyl-L-phenylalanine O-tert-butyl-L-tyrosine (Tby) p-iodo-L-phenylalanine Trifluoromethyl-L phenylalanine O-methyl-L-tyrosine
ACPK-RS RS/tRNA Pair Development Year 2011 ncAA(s) Incorporated N6-((2-azidoethoxy)carbonyl)-L-lysine N6-(((1R,2R)-2-azidocyclopentyloxy)carbonyl)-L-lysine (ACPK) BlocLys PlocLys N6-((Pent-4-yn-1-yloxy)carbonyl)-L-lysine
ZLysRS RS/tRNA Pair Development Year 2008 ncAA(s) Incorporated N6-(Benzyloxycarbonyl)-L-lysine (Z-Lys)
MmPylRS(Y306A,Y384F) RS/tRNA Pair Development Year 2008 ncAA(s) Incorporated Nε-(o Azidobenzyloxycarbon yl)-L-lysine (AzZLys) N6-(Benzyloxycarbonyl)-L-lysine (Z-Lys) 4'-TCOK (TCO) endo-BCN-L-Lysine exoBCN-L-Lysine 2'-axialTCOK (TCO*) TmdZLys pNO2ZLys N6-[2-(furan-2-yl)ethoxy]carbonyl Lys 2,2,5,5-tetramethyl-pyrrolin-1-oxyl
TCORS RS/tRNA Pair Development Year 2012 ncAA(s) Incorporated 4'-TCOK (TCO) Nε-(tert-Butoxycarbonyl)-L-lysine (BocLys)
