PylRS(N346A/C348A) RS/tRNA Pair Development Year 2012 ncAA(s) Incorporated 2-iodo-L-phenylalanine 2-chloro-L-phenylalanine 2-bromo-L-phenylalanine 2-methoxy-L-phenylalanine 2-Cyano-L-phenylalanine O-allyl-L-tyrosine O-Benzyl-L-tyrosine O-allyl-L-tyrosine O-propargyl-L-tyrosine 3-chloro-L-phenylalanine 3-bromo-L-phenylalanine 3-iodo-L-phenylalanine 3-methyl-L-phenylalanine 3-methoxy-L-phenylalanine 3-trifluoromethyl-L-phenylalanine 3-cyano-L-phenylalanine 3-nitro-L-phenylalanine 3-azido-L-phenylalanine
SepRS9/tRNA-SepA37 + EF-Sep21 (SepOTSλ) RS/tRNA Pair Development Year 2015 ncAA(s) Incorporated phosphoserine
AcKRS2 RS/tRNA Pair Development Year 2008 ncAA(s) Incorporated Nε-acetyl-L-lysine N6-Trifluoroacetyl-L-lysine
SepRS2/Sep-tRNA-v2 RS/tRNA Pair Development Year 2023 ncAA(s) Incorporated 2-amino-4-phosphonobutanoic acid (nhpSer)