PylRS-AS RS/tRNA Pair Development Year 2017 ncAA(s) Incorporated Pentafluoro-D-phenylalanine 2,3,4,5-tetrafluorophenylalanine 3,4,5-trifluorophenylalanine 3,5-difluorophenylalanine
NESPylRS RS/tRNA Pair Development Year 2017 ncAA(s) Incorporated Boc-LysOH N6-(Benzyloxycarbonyl)-L-lysine (Z-Lys) p-azido-L-phenylalanine (pAzF)
MmPylRS(IPYE) RS/tRNA Pair Development Year 2017 ncAA(s) Incorporated NĪµ-(tert-Butoxycarbonyl)-L-lysine (BocLys)
chPylRS(IPYE) RS/tRNA Pair Development Year 2017 ncAA(s) Incorporated NĪµ-(tert-Butoxycarbonyl)-L-lysine (BocLys)
MmPylRS-WT RS/tRNA Pair Development Year 2009 ncAA(s) Incorporated Pyrrolysine (Pyl) l-Cys-e-Lys D-Cys-Īµ-Lys (ā(S,S)ā) NĪµ-(Spiro[2.3]hex-1 ene-5 methoxycarbonyl)-L lysine NĪµ-Crotonyl-L-lysine NĪµ-Butyryl-L-lysine NĪµ-Propionyl-L-lysine N6-((2-azidoethoxy)carbonyl)-L-lysine(AzeoK) N6-(1-Methylcycloprop-2-enecarboxamido)lysine (CpK)
ZLysRS RS/tRNA Pair Development Year 2008 ncAA(s) Incorporated N6-(Benzyloxycarbonyl)-L-lysine (Z-Lys)
MmPylRS(Y306A,Y384F) RS/tRNA Pair Development Year 2008 ncAA(s) Incorporated NĪµ-(o Azidobenzyloxycarbon yl)-L-lysine (AzZLys) N6-(Benzyloxycarbonyl)-L-lysine (Z-Lys) 4'-TCOK (TCO) endo-BCN-L-Lysine exoBCN-L-Lysine 2'-axialTCOK (TCO*) TmdZLys pNO2ZLys N6-[2-(furan-2-yl)ethoxy]carbonyl Lys 2,2,5,5-tetramethyl-pyrrolin-1-oxyl
PylRS(N346A/C348A) RS/tRNA Pair Development Year 2012 ncAA(s) Incorporated 2-iodo-L-phenylalanine 2-chloro-L-phenylalanine 2-bromo-L-phenylalanine 2-methoxy-L-phenylalanine 2-Cyano-L-phenylalanine O-allyl-L-tyrosine O-methyl-L-tyrosine O-Benzyl-L-tyrosine O-allyl-L-tyrosine O-tert-butyl-L-tyrosine (Tby) O-propargyl-L-tyrosine O-3-butenyl-L-tyrosine O-4-pentenyl-L-tyrosine 3-chloro-L-phenylalanine 3-bromo-L-phenylalanine 3-iodo-L-phenylalanine 3-methyl-L-phenylalanine 3-methoxy-L-phenylalanine 3-trifluoromethyl-L-phenylalanine 3-cyano-L-phenylalanine 3-nitro-L-phenylalanine 3-acetyl-L-phenylalanine 3-allyl-L-phenylalanine 3-azido-L-phenylalanine 3-Formyl-L phenylalanine
