ncAA Database

Displaying 26 - 50 of 56 results
ncAA Name ncAA Structure ncAA Utility Moderation State
Norbornene-methoxycarbonyl-Lysine H-L-Lys(Norbornene-methoxycarbonyl)-OH Useful for click-chemistry with nitrile imines and tetrazines Published: Fully Reviewed
Norbornene-O–L-Lysine (NBO) Nε-5-Norbornene-2-yloxycarbonyl-L-lysine Reactive handle for IEDDA Published: Fully Reviewed
Nε-acetyl-L-lysine Image showing the ChemDraw Structure of Nε-Acetyl-L-lysine They are used for sites specifically studying post-translational modification acetylation events on particular lysine residues. Published: Under Review
O-3-butenyl-L-tyrosine (2S)-2-amino-3-(4-but-3-enoxyphenyl)propanoic acid n/a Published: Under Review
O-4-pentenyl-L-tyrosine O-4-pentenyl-L-tyrosine n/a Published: Under Review
O-allyl-L-tyrosine O-Allyl-L-tyrosine in E. coli expressed sfGFP2TAG at 10 mg/L using GMML media Published: Under Review
O-benzyl-L-serine O-benzyl-L-serine n/a Published: Under Review
O-methyl-L-tyrosine O-methyl-L-tyrosine Labelling of muscles
(global)
 Published: Under Review
o-nitro-L-phenylalanine 4-Nitro-3-phenyl-L-alanine Bioorthogonal Ligation handle Published: Under Review
O-propargyl-L-tyrosine O-propargyl-L-tyrosine Reactive handle for azide-alkyne cycloaddition Published: Under Review
O-tert-butyl-L-tyrosine (Tby) O-tert-butyl-L-tyrosine NMR tag for proteins Published: Fully Reviewed
p-amino-L-phenylalanine p-Aminophenylalanine π-donating effects, hydrogen-bonding properties, and weak basicity Published: Under Review
p-azido-L-phenylalanine (pAzF) Image showing the ChemDraw Structure of p-azido-l-phenylalanine (pAzF) Used as a photocrosslinker, allowing for crosslinking and bioorthogonal click-chemistry ligation of proteins via strain-promoted cycloadditions (SPAAC) with suitably functionalized molecules. Published: Under Review
p-benzoyl-L-phenylalanine (Bpa) Image showing the ChemDraw Structure of p-benzoyl-l-phenylalanine Used as a photocrosslinker, allowing for crosslinking and bioorthogonal ligation of protein. Published: Fully Reviewed
p-boronophenylalanine p-Boronophenylalanine enabled one-step "scarless" protein purification procedure, and can be used to site-specifically label proteins using various boronic acid chemistries. Also, in second foundational paper was used in creating a fluorescent probe for peroxinitrite. Published: Fully Reviewed
p-chloro-L-phenylalanine 4-Chloro-L-phenylalanine NMR probe Published: Under Review
p-fluoro-L-phenylalanine 4-Fluorophenylalanine NMR probe Published: Under Review
p-iodo-L-phenylalanine p-Iodo-L-phenylalanine Can be used for phasing in protein crystallography. Published: Under Review
p-trifluoroacetyl-L-phenylalanine 2-Amino-3-(4-(2,2,2-trifluoroacetyl)phenyl)propanoic acid Flourescent Probe, Bioorthogonal ligation handle Published: Under Review
phosphoserine pSer Used to produce proteins site-specifically phosphorylated at serine residues, typically at positions where phosphoserine naturally occurs as a post-translational modification Published: Fully Reviewed
phosphothreonine pThr Used to produce site-specifically phosphorylated proteins at a threonine residue via genetic code expansion. Published: Fully Reviewed
phosphotyrosine pTyr Used to produce site-specifically phosphorylated proteins at a tyrosine residue via genetic code expansion versus other protein phosphorylation strategies. Published: Under Review
pNO2ZLys para-nitro-ZLys Photo-­cross-linking agent, but no tests were done on this ncAA in the founding paper. Crosslinking experiments were only done with TmdZLys Published: Fully Reviewed
propargylglycine Propargylglycine copper-catalyzed alkyne-azide click chemistry (CuACC) can be used for time-resolved, cell-selective proteomic analyses Published: Fully Reviewed
S-Allylcysteine S-Allylcysteine Reactive cross-metathesis substrate Published: Under Review